The fabrication of an innovative extremely sensitive nano green carbon paste electrode amended with the nanocomposite CuO/Y for electrochemical quantification of amprolium in sheep meat and liver samples.

Autor: Elgazzar E; Department of Physics, Faculty of Science, Suez Canal, University, Ismailia, Egypt., Said RAM; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 11751, Nasr City, Cairo, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, 3 Cairo, Belbeis, Desert Road, Cairo, Egypt., El-Zomrawy AA; Chemistry Department, Faculty of Science (boys), Al-Azhar University, 11884, Egypt., Ashmawy AM; Chemistry Department, Faculty of Science (boys), Al-Azhar University, 11884, Egypt., Abdel-Raoof AM; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 11751, Nasr City, Cairo, Egypt. Electronic address: Ahmedmeetyazeed79@Azhar.edu.eg., Mostafa WA; Entomolgy Section, Zoology Department, Faculty of Science, Zagazig University, Zagazig, Egypt., Ibrahim H; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt., El-Attar AMM; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, 11751, Nasr City, Cairo, Egypt. Electronic address: Abdul.azizalattar@azhar.edu.eg.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2022 Aug 15; Vol. 385, pp. 132668. Date of Electronic Publication: 2022 Mar 09.
DOI: 10.1016/j.foodchem.2022.132668
Abstrakt: In this work, carbon paste electrode (CPE) and modified CPE with copper oxide or copper yttrium oxide were prepared for determining amprolium hydrochloride (AMP) by differential pulse voltammetry. AMP has an antiprotozoal activity for treating coccidiosis in poultry; their retaining- in sheep meat and livers- induces adversative effects for the customer. XRD pattern was employed to define the fabricated nanostructured materials; the elemental composition of the nanocomposite was examined using EDX spectra. Over a pH ranging from 2 to 8, the oxidation process of AMP was studied using phosphate buffer. The scan rates were studied over a wide range (20 to 140 mV s -1 ) using cyclic voltammetry. The developed sensor shows a wide linear range (1.0 × 10 -8 -1.0 × 10 -3 M) with a detection limit of 2.32 × 10 -9 M. This method can quantify AMP in pharmaceutical form, sheep meat, and liver samples.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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