Genetic mechanisms of aging in plants: What can we learn from them?

Autor: Popov VN; Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russian Federation. Electronic address: pvn@vsuet.ru., Syromyatnikov MY; Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russian Federation. Electronic address: syromyatnikov@bio.vsu.ru., Franceschi C; Department of Experimental, Diagnostic, and Specialty Medicine (DIMES), University of Bologna, 40126 Bologna, Italy; Laboratory of Systems Biology of Healthy Aging, Department of Applied Mathematics and Center of Bioinformatics, Institute of Information Technologies, Mathematics and Mechanics, Lobachevsky State University, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russian Federation. Electronic address: claudio.franceschi@unibo.it., Moskalev AA; Institute of Biology, Federal Research Center, Komi Scientific Center, Ural Branch of Russian Academy of Sciences, 167000 Syktyvkar, Russian Federation; Russian Clinical and Research Center of Gerontology, Pirogov Russian National Research Medical University, 1st Leonova Street, 129226 Moscow, Russian Federation. Electronic address: amoskalev@ib.komisc.ru., Krutovsky KV; Department of Forest Genetics and Forest Tree Breeding, Georg-August University of Göttingen, Büsgenweg 2, D-37077 Göttingen, Germany; Center for Integrated Breeding Research (CiBreed), Georg-August University of Göttingen, Albrecht-Thaer-Weg 3, D-37075 Göttingen, Germany; Laboratory of Population Genetics, N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, 3 Gubkin Street, 119333 Moscow, Russian Federation; Laboratory of Forest Genomics, Genome Research and Education Center, Department of Genomics and Bioinformatics, Siberian Federal University, 660036 Krasnoyarsk, Russian Federation; Scientific and Methodological Center, G. F. Morozov Voronezh State University of Forestry and Technologies, 8 Timiryazeva Street, 394036 Voronezh, Russian Federation. Electronic address: konstantin.krutovsky@forst.uni-goettingen.de.
Jazyk: angličtina
Zdroj: Ageing research reviews [Ageing Res Rev] 2022 May; Vol. 77, pp. 101601. Date of Electronic Publication: 2022 Mar 09.
DOI: 10.1016/j.arr.2022.101601
Abstrakt: Plants hold all records in longevity. Their aging is a complex process. In the presented review, we analyzed published data on various aspects of plant aging with focus on any inferences that could shed a light on aging in animals and help to fight it in human. Plant aging can be caused by many factors, such as telomere depletion, genomic instability, loss of proteostasis, changes in intercellular interaction, desynchronosis, autophagy misregulation, epigenetic changes and others. Plants have developed a number of mechanisms to increase lifespan. Among these mechanisms are gene duplication ("genetic backup"), the active work of telomerases, abundance of meristematic cells, capacity of maintaining the meristems permanently active and continuous activity of phytohormones. Plant aging usually occurs throughout the whole perennial life, but could be also seasonal senescence. Study of causes for seasonal aging can also help to uncover the mechanisms of plant longevity. The influence of different factors such as microbiome communities, glycation, alternative oxidase activity, mitochondrial dysfunction on plant longevity was also reviewed. Adaptive mechanisms of long-lived plants are considered. Further comparative study of the mechanisms underlying longevity of plants is necessary. This will allow us to reach a potentially new level of understanding of the aging process of plants.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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