| Autor: |
da Cruz SP; Center for Research on Micronutrients, Federal University of Rio de Janeiro (NPqM/UFRJ), Rio de Janeiro 21941-902, Brazil., Cruz S; Center for Research on Micronutrients, Federal University of Rio de Janeiro (NPqM/UFRJ), Rio de Janeiro 21941-902, Brazil., Pereira S; Multidisciplinary Center for Bariatric and Metabolic Surgery, Federal University of Rio de Janeiro (NPqM/UFRJ), Rio de Janeiro 21941-902, Brazil., Saboya C; Brazilian Society of Bariatric and Metabolic Surgery, Rio de Janeiro 22280-020, Brazil., Lack Veiga JC; Center for Research on Micronutrients, Federal University of Fluminense, Rio de Janeiro 24220-008, Brazil., Ramalho A; Center for Research on Micronutrients, Federal University of Rio de Janeiro (NPqM/UFRJ), Rio de Janeiro 21941-902, Brazil. |
| Abstrakt: |
Evaluating the influence of vitamin D concentrations together with preoperative metabolic phenotypes on remission of chronic noncommunicable diseases (CNCDs) after 6 months of Roux-en-Y gastric bypass (RYGB). Cross-sectional analytical study comprising 30 adult individuals who were assessed preoperatively (T0) and 6 months (T1) after undergoing RYGB. Participants were distributed preoperatively into metabolically healthy obese (MHO) and metabolically unhealthy obese (MUHO) individuals according to HOMA-IR classification and to the adequacy and inadequacy of vitamin D concentrations in the form of 25(OH)D. All participants were assessed for anthropometric characteristics, biochemical variables, and presence of CNCDs. The statistical program used was the SPSS version 21. In face of vitamin D adequacy and regardless of the metabolic phenotype classification in the preoperative period, the means found for HOMA-IR allowed us to define them as metabolically healthy 6 months after RYGB. Only those with vitamin D inadequacy with the MUHO phenotype showed better results regarding the reduction of glucose that accompanied the shift in serum 25(OH)D concentrations from deficient to insufficient. It is possible that preoperative vitamin D adequacy, even in the presence of an unhealthy phenotype, may contribute to the reduction of dyslipidemia and improvement in cholesterol. It is suggested that preoperative vitamin D adequacy in both phenotypes may have a protective effect on metabolic health. |
