| Autor: |
Darras A; Experimental Physics, Saarland University, 66123 Saarbruecken, Germany., Dasanna AK; Theoretical Physics of Living Matter, Institute of Biological Information Processing and Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany., John T; Experimental Physics, Saarland University, 66123 Saarbruecken, Germany., Gompper G; Theoretical Physics of Living Matter, Institute of Biological Information Processing and Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany., Kaestner L; Experimental Physics, Saarland University, 66123 Saarbruecken, Germany.; Theoretical Medicine and Biosciences, Saarland University, 66424 Homburg, Germany., Fedosov DA; Theoretical Physics of Living Matter, Institute of Biological Information Processing and Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany., Wagner C; Experimental Physics, Saarland University, 66123 Saarbruecken, Germany.; Department of Physics and Materials Science, University of Luxembourg, L-1511, Luxembourg City, Luxembourg. |
| Abstrakt: |
The erythrocyte sedimentation rate is one of the oldest medical diagnostic methods whose physical mechanisms remain debatable today. Using both light microscopy and mesoscale cell-level simulations, we show that erythrocytes form a soft-particle gel. Furthermore, the high volume fraction of erythrocytes, their deformability, and weak attraction lead to unusual properties of this gel. A theoretical model for the gravitational collapse is developed, whose predictions are in agreement with detailed macroscopic measurements of the interface velocity. |
