| Autor: |
Meneses J; LEPABE, Faculdade de Engenharia, Universidade do Porto, Rua Roberto Frias, 4200-465 Porto, Portugal.; International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal., van de Kemp T; LEPABE, Faculdade de Engenharia, Universidade do Porto, Rua Roberto Frias, 4200-465 Porto, Portugal.; i3S-Instituto de Investigação e Inovacão em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; INEB-Instituto de Engenharia Biomédica, Universidade do Porto, 4200-135 Porto, Portugal.; Department of Orthopedics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Costa-Almeida R; i3S-Instituto de Investigação e Inovacão em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; INEB-Instituto de Engenharia Biomédica, Universidade do Porto, 4200-135 Porto, Portugal., Pereira R; i3S-Instituto de Investigação e Inovacão em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; INEB-Instituto de Engenharia Biomédica, Universidade do Porto, 4200-135 Porto, Portugal.; ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal., Magalhães FD; LEPABE, Faculdade de Engenharia, Universidade do Porto, Rua Roberto Frias, 4200-465 Porto, Portugal., Castilho M; Department of Orthopedics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.; Department of Biomedical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands., Pinto AM; LEPABE, Faculdade de Engenharia, Universidade do Porto, Rua Roberto Frias, 4200-465 Porto, Portugal.; i3S-Instituto de Investigação e Inovacão em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.; INEB-Instituto de Engenharia Biomédica, Universidade do Porto, 4200-135 Porto, Portugal. |
| Abstrakt: |
Graphene-based materials (GBM) are considered one of the 21st century's most promising materials, as they are incredibly light, strong, thin and have remarkable electrical and thermal properties. As a result, over the past decade, their combination with a diverse range of synthetic polymers has been explored in tissue engineering (TE) and regenerative medicine (RM). In addition, a wide range of methods for fabricating polymer/GBM scaffolds have been reported. This review provides an overview of the most recent advances in polymer/GBM composite development and fabrication, focusing on methods such as electrospinning and additive manufacturing (AM). As a future outlook, this work stresses the need for more in vivo studies to validate polymer/GBM composite scaffolds for TE applications, and gives insight on their fabrication by state-of-the-art processing technologies. |
