Severe α 1 -antitrypsin deficiency associated with lower blood pressure and reduced risk of ischemic heart disease: a cohort study of 91,540 individuals and a meta-analysis.
Autor: | Winther SV; Department of Clinical Biochemistry, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark., Ahmed D; Department of Clinical Biochemistry, Zealand University Hospital, Køge, Denmark., Al-Shuweli S; Department of Clinical Biochemistry, Zealand University Hospital, Køge, Denmark., Landt EM; Department of Clinical Biochemistry, Zealand University Hospital, Køge, Denmark., Nordestgaard BG; Department of Clinical Biochemistry, Herlev-Gentofte University Hospital, Herlev, Denmark.; The Copenhagen General Population Study, Herlev-Gentofte University Hospital, Herlev, Denmark.; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark., Seersholm N; Department of Pulmonary Medicine, Herlev-Gentofte University Hospital, Gentofte, Denmark., Dahl M; Department of Clinical Biochemistry, Zealand University Hospital, Køge, Denmark. modah@regionsjaelland.dk.; The Copenhagen General Population Study, Herlev-Gentofte University Hospital, Herlev, Denmark. modah@regionsjaelland.dk.; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark. modah@regionsjaelland.dk. |
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Jazyk: | angličtina |
Zdroj: | Respiratory research [Respir Res] 2022 Mar 09; Vol. 23 (1), pp. 55. Date of Electronic Publication: 2022 Mar 09. |
DOI: | 10.1186/s12931-022-01973-3 |
Abstrakt: | Background: Increased elastase activity in α Methods: We genotyped 91,353 adults randomly selected from the Danish general population and 187 patients from the Danish α Results: α Conclusions: Individuals with severe α (© 2022. The Author(s).) |
Databáze: | MEDLINE |
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