Forearm and Hand Muscles Exhibit High Coactivation and Overlapping of Cortical Motor Representations.

Autor: Tardelli GP; Department of Physics, School of Philosophy, Science and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil., Souza VH; Department of Physics, School of Philosophy, Science and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. victor.souza@aalto.fi.; Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland. victor.souza@aalto.fi.; Graduate Program in Rehabilitation Sciences and Functional Physical Performance, School of Physiotherapy, Federal University of Juiz de Fora, Juiz de Fora, Brazil. victor.souza@aalto.fi., Matsuda RH; Department of Physics, School of Philosophy, Science and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.; Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland., Garcia MAC; Department of Physics, School of Philosophy, Science and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.; Graduate Program in Rehabilitation Sciences and Functional Physical Performance, School of Physiotherapy, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Neuro Biomechanics Group, School of Physiotherapy, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Novikov PA; Centre for Cognition and Decision Making, Institute for Cognitive Neuroscience, National Research University Higher School of Economics, Moscow, Russian Federation., Nazarova MA; Centre for Cognition and Decision Making, Institute for Cognitive Neuroscience, National Research University Higher School of Economics, Moscow, Russian Federation.; Federal State Budgetary Institution «Federal Center of Brain Research and Neurotechnologies» of the Federal Medical Biological Agency, Moscow, Russian Federation., Baffa O; Department of Physics, School of Philosophy, Science and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
Jazyk: angličtina
Zdroj: Brain topography [Brain Topogr] 2022 May; Vol. 35 (3), pp. 322-336. Date of Electronic Publication: 2022 Mar 09.
DOI: 10.1007/s10548-022-00893-1
Abstrakt: Most of the motor mapping procedures using navigated transcranial magnetic stimulation (nTMS) follow the conventional somatotopic organization of the primary motor cortex (M1) by assessing the representation of a particular target muscle, disregarding the possible coactivation of synergistic muscles. In turn, multiple reports describe a functional organization of the M1 with an overlapping among motor representations acting together to execute movements. In this context, the overlap degree among cortical representations of synergistic hand and forearm muscles remains an open question. This study aimed to evaluate the muscle coactivation and representation overlapping common to the grasping movement and its dependence on the stimulation parameters. The nTMS motor maps were obtained from one carpal muscle and two intrinsic hand muscles during rest. We quantified the overlapping motor maps in size (area and volume overlap degree) and topography (similarity and centroid Euclidean distance) parameters. We demonstrated that these muscle representations are highly overlapped and similar in shape. The overlap degrees involving the forearm muscle were significantly higher than only among the intrinsic hand muscles. Moreover, the stimulation intensity had a stronger effect on the size compared to the topography parameters. Our study contributes to a more detailed cortical motor representation towards a synergistic, functional arrangement of M1. Understanding the muscle group coactivation may provide more accurate motor maps when delineating the eloquent brain tissue during pre-surgical planning.
(© 2022. The Author(s).)
Databáze: MEDLINE
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