Early detection of community acquired of SARS-CoV-2 lineage B.1.351 in Hong Kong.

Autor:	Tsang AKL; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Mak GCK; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Cheng PKC; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Yip PCW; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Ng KHL; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Lam ETK; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Chan RCW; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region., Tsang DNC; All from Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, 9/F, Public Health Laboratory center, 382 Nam Cheong Street, Shek Kip Mei, Kowloon, Hong Kong Special Administrative Region.
Jazyk:	angličtina
Zdroj:	Journal of clinical virology plus [J Clin Virol Plus] 2021 Sep; Vol. 1 (3), pp. 100029. Date of Electronic Publication: 2021 Jun 14.
DOI:	10.1016/j.jcvp.2021.100029
Abstrakt:	Background: Prior to this report, variants of concern for SARS-CoV-2 were only detected from imported cases in Hong Kong. Objective: Multiple cases of SARS-CoV-2 lineage B.1.351 have been identified in local community. We reported the phylogenetic relationship of these cases. Study Design: SARS-CoV-2 cases were screened for the key non-synonymous substitutions in spike protein by different assays. Preliminary positive cases were further tested by whole genome sequencing. Results: From Dec 2020 to May 2021, 55 SARS-CoV-2 cases belonged to lineage B.1.351. Among them, eight genomes were clustered together, all of them were local cases with epidemiological link. Conclusions: To track variants of SARS-CoV-2 and to allow early implementation of control measures, SARS-CoV-2 genomic surveillance must be consistently performed. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2021 The Authors.)
Databáze:	MEDLINE
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