Concomitance or consequence? Stevens-Johnson syndrome in COVID-19: A case report.

Autor: Manciuc C; Department of Infectious Diseases, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania., Lacatusu GA; Department of Infectious Diseases, Sf. Parascheva Clinical Hospital of Infectious Diseases, 700116 Iasi, Romania., Vata A; Department of Infectious Diseases, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania., Sapaniuc C; Department of Infectious Diseases, Sf. Parascheva Clinical Hospital of Infectious Diseases, 700116 Iasi, Romania., Arteni CM; Department of Infectious Diseases, Sf. Parascheva Clinical Hospital of Infectious Diseases, 700116 Iasi, Romania., Petrariu FD; Department of Preventive Medicine and Interdisciplinary, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Jazyk: angličtina
Zdroj: Experimental and therapeutic medicine [Exp Ther Med] 2022 Apr; Vol. 23 (4), pp. 257. Date of Electronic Publication: 2022 Feb 02.
DOI: 10.3892/etm.2022.11182
Abstrakt: The novel coronavirus infection has been, and still is, a pressing medical problem with a catastrophic effect, not only from a medical point of view, but also from an economic and social one. The cutaneous manifestations of the disease have a diverse morphology and can signal the presence of the infection. The present article reports the case of a 77-year-old male patient admitted at The Sf. Parascheva Clinical Hospital of Infectious Diseases in Iasi (Romania) after testing positive for SARS CoV-2 infection. Initially, the patient presented a pruriginous generalized maculopapular-erythematous eruption with a tendency towards confluence, peri-oro-nasal meliceric crusts and desquamation of the skin on the third anterosuperior and posterior thorax, scalp and forehead, which was accompanied by low back pain, headache and orbital pain. The suspicion of Stevens-Johnson syndrome (SJS) was raised, and treatment was given according to the recommendation of the hospital dermatologist. This association raises multiple questions regarding whether SJS is a cutaneous manifestation of COVID-19 or if there was a concomitance between the viral infection and the immune reaction. The combination of SJS and COVID-19 can have a fatal outcome if not recognized and promptly treated. To our knowledge, this is the first case of SJS in a patient diagnosed with SARS CoV-2 infection in Romania.
Competing Interests: The authors declare that they have no competing interests.
(Copyright: © Manciuc et al.)
Databáze: MEDLINE
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