Desensitization to drugs in children.

Autor: Ensina LF; Department of Pediatrics, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil; 100alergia@gmail.com., Felix MMR; Department of General Medicine, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil., da Cunha FS; Department of General Medicine, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil., Caubet JC; Department of Child and Adolescent, Geneva University Hospitals, Geneva, Switzerland.
Jazyk: angličtina
Zdroj: Allergologia et immunopathologia [Allergol Immunopathol (Madr)] 2022 Mar 01; Vol. 50 (2), pp. 48-57. Date of Electronic Publication: 2022 Mar 01 (Print Publication: 2022).
DOI: 10.15586/aei.v50i2.539
Abstrakt: Better knowledge and understanding about drug desensitization is required in the pediatric population, since there is little literature available about it and the most pediatric desensitization protocols have been adapted from adult instructions.Aiming to soften this issue and foster the future studies, this article presents a recent review about mechanisms of desensitization, diagnostic tools, and up to date management of drug hypersensitivity reactions in children. Bringing up an overview of pediatric hypersensitivity reactions to chemotherapy, biologic agents, antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines.
Databáze: MEDLINE