Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience.

Autor:	Le Minh K; Vietnam National University, Hanoi (VNU), National Otorhinolaryngology Hospital of Vietnam, Hanoi, Vietnam., Nguyen Dinh P; ENT Department, Hanoi Medical University, Hanoi, Vietnam., Doan Thi Hong N; ENT Department, Vinh Medical University, Nghe An, Vietnam., Pham Van H; Department of Head and Neck Surgery, National Otorhinolaryngology Hospital of Vietnam, Hanoi, Vietnam., Nguyen Xuan Q; Department of Head and Neck Surgery, National Otorhinolaryngology Hospital of Vietnam, Hanoi, Vietnam., Nguyen Xuan H; ENT Department, Vietnam University of Traditional Medicine, Hanoi, Vietnam., Nguyen Thi To U; ENT Department, Hanoi Medical University, Hanoi, Vietnam.
Jazyk:	angličtina
Zdroj:	International journal of general medicine [Int J Gen Med] 2022 Mar 01; Vol. 15, pp. 2321-2328. Date of Electronic Publication: 2022 Mar 01 (Print Publication: 2022).
DOI:	10.2147/IJGM.S350624
Abstrakt:	Aim: Laryngeal cancer is a common form of head and neck cancer in Vietnam where the current treatment is surgery. Subtotal laryngectomy with epiglottic reconstruction, a conservative surgery, allows removal of anterior commissure including thyroid cartilage and paraglottic space and provides a maximum restoration of the anatomical structure of the larynx. Purpose: To evaluate the results, the safety and effectiveness of patients who were treated with subtotal laryngectomy with epiglottic reconstruction. Material and Method: From January 2012 to July 2017, 42 patients (41 male, 1 female, median age 55.6 years, range 38-75 years) were diagnosed with glottic carcinomas at Vietnam National ENT Hospital, where they underwent a subtotal laryngectomy with epiglottic reconstruction. Results: Thirty-one patients (73.8%) had T2 glottic carcinoma, 4 (9.5%) T3 glottic carcinoma, and 12 (25.6%) had neck dissection. The arytenoid cartilage on the tumor-bearing side was resected in 11 patients (26.2%). Functional ipsilateral neck dissection was performed in 30 patients. Positive lymph node of stage T2 was 1/31 (3.2%). Postoperative histopathologic examination showed a tumour free of resection margin in 41 patients (97.6%). Only one post-operative complication occurred with bleeding 24 hours after surgery. There was no mortality. The 3- and 5-year overall survival rates were 97.6% and 85.7%, respectively. The rate of local control was 92.9%. Conclusion: Subtotal laryngectomy with epiglottic reconstruction was performed mostly for T2 and certain T3 glottic carcinomas when there is difficult to safely remove the tumour with transoral laser microsurgery. This surgery appears to be effective for the overall survival and has potential in clinical practice for treating moderate glottic carcinoma. Competing Interests: The authors declare that they have no potential conflicts of interest for this work. (© 2022 Le Minh et al.)
Databáze:	MEDLINE
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