Collagen/Nano-hydroxyapatite Composite Scaffold Application with Exchange Reamed Nailing Accelerates Bone Union and Improves Quality of Life in Atrophic Femoral Shaft Nonunions: A Retrospective Comparative Study.

Autor: Gönder N; Department of Orthopaedics and Traumatology, T.C. Ministry of Health Islahiye State Hospital, 27800 Gaziantep, Turkey., Demir İH; Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, 27310 Gaziantep, Turkey., Öğümsöğütlü E; Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, 27310 Gaziantep, Turkey., Kılınçoğlu V; Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, 27310 Gaziantep, Turkey.
Jazyk: angličtina
Zdroj: Indian journal of orthopaedics [Indian J Orthop] 2021 Oct 19; Vol. 56 (3), pp. 412-420. Date of Electronic Publication: 2021 Oct 19 (Print Publication: 2022).
DOI: 10.1007/s43465-021-00545-9
Abstrakt: Background: Our aim in this study was to evaluate the effect of exchange intramedullary nailing in femoral shaft atrophic nonunions and the use of collagen/nano-hydroxyapatite composite scaffold applied in addition to the cancellous iliac crest autograft on the union, return to work, and quality of life.
Materials and Methods: Fifty-four patients with an atrophic nonunion in the isthmic region of the femoral shaft were included in the study. The patients were divided into two groups. Group A consisted of 24 patients who underwent collagen/nano-hydroxyapatite composite scaffold in addition to exchange intramedullary nailing and iliac autograft, while group B consisted of 30 patients without scaffold. Short Form-36 (SF-36) questionnaire scores, union rates, time to union, return to work were complications were compared.
Results: Mean age of patients was 47.5 ± 14.1. The mean follow-up period was 3.56 ± 1.88 years. There was no statistically significant difference between Group A and B in terms of age, gender, smoking and alcohol use, and trauma mechanism. Time to union and return to work were statistically significantly shorter in Group A than in Group B ( p  = 0.004, p  = 0.001). All of the SF-36 survey scores at month six were better in Group A. In the first year, mental health and general health perception were still statistically better in group A ( p  = 0.009, p  = 0.008).
Conclusion: In the treatment of atrophic nonunions of the femoral shaft isthmic region, the use of collagen/nano-hydroxyapatite composite scaffolds together with exchange intramedullary nailing affects the union positively. This positive effect also brings about earlier return to work and better quality of life.
Competing Interests: Conflict of interestThe authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© Indian Orthopaedics Association 2021.)
Databáze: MEDLINE
Externí odkaz: