CT evaluation of lung infiltrates in the two months preceding the Coronavirus disease 19 pandemic in Canton Ticino (Switzerland): were there suspicious cases before the official first case?

Autor: Rizzo S; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland. Stefania.rizzo@eoc.ch.; Facoltà Di Scienze Biomediche, Università della Svizzera italiana (USI), Lugano, Switzerland. Stefania.rizzo@eoc.ch., Catanese C; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland., Puligheddu C; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland., Epistolio S; Istituto Cantonale Di Patologia (ICP), Ente Ospedaliero Cantonale (EOC), Locarno, Switzerland., Ramelli G; Istituto Cantonale Di Patologia (ICP), Ente Ospedaliero Cantonale (EOC), Locarno, Switzerland., Frattini M; Istituto Cantonale Di Patologia (ICP), Ente Ospedaliero Cantonale (EOC), Locarno, Switzerland., Pereira Mestre R; Service of Medical Oncology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland., Nadarajah N; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland., Rezzonico E; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland., Magoga F; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland., Milan L; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland., Del Grande F; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland.; Facoltà Di Scienze Biomediche, Università della Svizzera italiana (USI), Lugano, Switzerland., Giovanella L; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland.; University Hospital of Zurich, Zurich, Switzerland., Ceriani L; Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900, Lugano, Switzerland.; Facoltà Di Scienze Biomediche, Università della Svizzera italiana (USI), Lugano, Switzerland.
Jazyk: angličtina
Zdroj: La Radiologia medica [Radiol Med] 2022 Apr; Vol. 127 (4), pp. 360-368. Date of Electronic Publication: 2022 Mar 05.
DOI: 10.1007/s11547-022-01466-9
Abstrakt: Purpose: The main objective of this study was to assess the presence of pulmonary infiltrates with computed tomography (CT) appearance compatible with infection by coronavirus disease 2019 (COVID-19), in Canton Ticino in the 2 months preceding the first official case. Secondary aims were to compare the classification of infiltrates in the same time frame in 2020 and 2019; to compare the number of chest CT scans in the same period; to search for pathological confirmation of the virus.
Materials and Methods: Chest CT scans performed between January 1 and February 24 in 2019 and 2020 were collected and classified by COVID-19 Reporting and Data System (CO-RADS). Pathological presence of the virus was searched for when appropriate material was available.
Results: The final cohort included 881 patients. Among the CO-RADS 3 and 4 categories, 30 patients had pneumonitis of unknown etiology. Pathological specimens were available in six patients but they were negative for COVID-19.
Conclusion: Before the first official case of COVID-19 infection, in Canton Ticino there were about 30 cases of pneumonitis of uncertain origin, with CT appearance compatible with infection by COVID-19, but with no confirmation of the disease. The number of chest CT scans in the first two months of 2020 was > 12% compared to 2019.
(© 2022. The Author(s).)
Databáze: MEDLINE
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