Autor: |
Kahn F; Department of Clinical Sciences Lund, Section for Infection Medicine, Skåne University Hospital, Lund University, Lund, Sweden., Bonander C; School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden., Moghaddassi M; Social Medicine and Global Health, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Rasmussen M; Department of Clinical Sciences Lund, Section for Infection Medicine, Skåne University Hospital, Lund University, Lund, Sweden., Malmqvist U; Clinical Studies Sweden, Forum South, Skåne University Hospital, Lund, Sweden., Inghammar M; Department of Clinical Sciences Lund, Section for Infection Medicine, Skåne University Hospital, Lund University, Lund, Sweden., Björk J; Clinical Studies Sweden, Forum South, Skåne University Hospital, Lund, Sweden.; Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden. |
Abstrakt: |
We compared the risk of severe COVID-19 during two periods 2021 and 2022 when Delta and Omicron, respectively, were the dominating virus variants in Scania county, Sweden. We adjusted for differences in sex, age, comorbidities, prior infection and vaccination. Risk of severe disease from Omicron was markedly lower among vaccinated cases. It was also lower among the unvaccinated but remained high (> 5%) for older people and middle-aged men with two or more comorbidities. Efforts to increase vaccination uptake should continue. |