Autor: |
Efendiev AM, Pomoĭnetskiĭ VD, Smirnov LD, Kubatiev AA |
Jazyk: |
ruština |
Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1986 May-Jun; Vol. 49 (3), pp. 60-3. |
Abstrakt: |
The effects of L-tocopherol and synthetic antioxidants on synthesis of prostaglandins, thromboxane B2 and prostacyclin in different layers of the kidney against the background of chronic administration of polyene antibiotics (amphotericin B, levorin, nystatin) were studied in the experiments on aged rats. It was concluded that synthetic antioxidants regulate synthesis of these biologically active substances and also are able to protect the organ from the damaging effect of polyene antibiotics. |
Databáze: |
MEDLINE |
Externí odkaz: |
|