Reproducibility, validity, and reliability of the incremental step test for subjects with moderate to severe asthma.

Autor: Barbosa RCC; Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil., Silva RA; Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil., Lunardi AC; Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil., Silva STC; Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil., Corso SD; Graduate Program in Rehabilitation Sciences, Universidade Nove de Julho, São Paulo, Brazil., Fonseca AJ; Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil., Stelmach R; Pulmonary Division, Heart Institute (InCor), Clinical Hospital, Medical School, University of Sao Paulo, Sao Paulo, Brazil., Carvalho CRF; Department of Physical Therapy, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil. Electronic address: cscarval@usp.br.
Jazyk: angličtina
Zdroj: Pulmonology [Pulmonology] 2024 Jul-Aug; Vol. 30 (4), pp. 344-351. Date of Electronic Publication: 2022 Feb 24.
DOI: 10.1016/j.pulmoe.2022.02.002
Abstrakt: Objective: We investigated the measurement properties of the incremental step test in subjects with moderate to severe asthma.
Methods: Subjects with moderate to severe persistent asthma were recruited from a tertiary university hospital specializing in treating severe asthma. All subjects performed one cardiopulmonary exercise test (CPET) and two incremental step tests (IST) in random sequences. Pulmonary gas exchange was measured during all exercise tests. The measurement properties investigated were reliability by intraclass correlation coefficient (ICC), measurement error by the standard error of measurement and minimum detectable difference, construct validity by Pearson's correlation, and interpretability by the ceiling and floor effects.
Results: Fifty subjects (38 females, mean [SD], age 43.7 [11.6] yr, % FEV 1 70 [14.3], BMI 28.5 [5.3] kg/m 2 ) completed the study. The peak oxygen uptake (peak VO 2 ) for the CPET was 27.6 [±6.8] ml/kg/min, for the first IST was 22.3 [±5.3] ml/kg/min and for the second IST was 23.3 [±5.3] ml/kg/min. The IST presented excellent reliability (ICC=0.93, CI95% 0.88-0.96), very good measurement error (2.5%), and construct validity for peak VO 2 measurement compared to the CPET (r = 0.85; p < 0.001) to assess exercise capacity in subjects with moderate to severe asthma, with appropriate ceiling (10%) and floor (0%) effects.
Conclusion: The IST presented excellent reliability and very good measurement error and validity to assess exercise capacity in subjects with moderate to severe asthma, without ceiling or floor effects.
Competing Interests: Decleration of competing interest All authors declare no conflicts of interest.
(Copyright © 2022 Sociedade Portuguesa de Pneumologia. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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