| Autor: |
Lin HY; Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu 30062, Taiwan., Liao JW; Graduate Institute of Veterinary Pathobiology, National Chung Hsing University, Taichung 40227, Taiwan.; Graduate Institute of Food Safety, National Chung Hsing University, Taichung 40227, Taiwan., Chen RS; Graduate Institute of Veterinary Pathobiology, National Chung Hsing University, Taichung 40227, Taiwan., Chang CH; Graduate Institute of Food Safety, National Chung Hsing University, Taichung 40227, Taiwan., Chang HW; Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu 30062, Taiwan., Chang SC; Department of Veterinary Medicine, National Chung Hsing University, Taichung 40227, Taiwan., Chu WS; Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu 30062, Taiwan., Lin CK; Department of Food Science and Technology, Hung Kuang University, Taichung 43302, Taiwan., Lin HT; Graduate Institute of Food Safety, National Chung Hsing University, Taichung 40227, Taiwan.; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung 40227, Taiwan. |
| Abstrakt: |
Although the safety of commercial genetically modified (GM) soybeans has been well evaluated and GM soybeans are legally sold under government management, some consumers still have concerns about their safety. The objective of this study was to evaluate the safety of commercial GM soybeans sold in markets as a food source. In the present study, two commercial GM (GM-1 and -2) soybeans and one non-GM soybean were randomly purchased and subjected to a whole food toxicity assessment. Rats (SD), male and female, were divided into six groups (10/sex/group). Two dosages of 1 g/kg/day and 5 g/kg/day of soybeans were selected for the low- and high-dose groups. Rats were administered the soybeans via daily oral fed for 90 days. The results indicate that the body weight, organ weight, biochemistry, hematology, and urology showed no biologically adverse effects. At necropsy, no significant differences between organ weights were noted between the non-GM- and GM soybeans-treated groups. Moreover, no gross or histopathological lesions were observed in the high-dosage (5 g/kg/day) fed groups of the non-GM and GM soybean fed rats. In conclusion, this food safety assessment revealed that commercial GM soybeans are substantially equivalent to non-GM soybeans in rats. |
