Autor: |
Tsai J; Department of Neuroscience, Brown University, Providence, RI 02912, USA., Lai JY; Department of Pediatric Surgery, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan., Lin YH; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan., Tsai MH; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan., Yeh PJ; Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan., Chen CL; Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan., Chang YJ; College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.; Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan. |
Abstrakt: |
Identifying ischemic ovary as a complication of ovary torsion (OT) is a significant challenge in children. This study identified risk factors for ischemic OT among pediatric OT patients to prevent delayed treatment. This retrospective study included pediatric inpatients who underwent operation for OT over 20 years. We employed multivariable logistic regression to find the risk factors associated with ischemic OT. Among the 118 patients included in this study, 78 (66.1%) had ischemic OT. Patients with ischemic OT tended to be younger; had more frequent vomiting; and had elevated White blood cell (WBC), C-Reactive protein (CRP), and segments in comparison with non-ischemic OT patients. Multivariable regression showed increased odds of ischemic ovary torsion, associated with higher WBC (12.3 × 10 3 /mm 3 vs. 8.7 × 10 3 /mm 3 , p < 0.001), CRP (50.4 mg/L vs. 8.4 mg/L, p < 0.001), and vomiting (55.1% vs. 25%, p = 0.002) than in non-ischemic patients. A receiver-operating characteristic (ROC) analysis indicated that patients with vomiting, leukocytosis, or CRP ≧ 40 mg/L were more likely to have ischemic OT (sensitivity, 92%; specificity, 54%; PPV, 79.6; NPV, 78.9%). Ischemic OT is common among pediatric OT patients. The presence of potential risk factors of vomiting, leukocytosis, and CRP more significant than 40 mg/L may assist clinicians in ensuring an expedited surgical treatment. |