Point Prevalence Survey of Antibiotic Use across 13 Hospitals in Uganda.

Autor:	Kiggundu R; USAID Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, Management Sciences for Health (MSH), Kampala P.O. Box 920102, Uganda., Wittenauer R; School of Pharmacy, University of Washington, Seattle, WA 98105, USA., Waswa JP; USAID Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, Management Sciences for Health (MSH), Kampala P.O. Box 920102, Uganda., Nakambale HN; Department of Global Health, University of Washington, Seattle, WA 98105, USA., Kitutu FE; Sustainable Pharmaceutical Systems (SPS) Unit, Pharmacy Department, Makerere University School of Health Sciences, Kampala P.O. Box 10217, Uganda., Murungi M; USAID Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, Management Sciences for Health (MSH), Kampala P.O. Box 920102, Uganda., Okuna N; Department of Pharmaceuticals and Natural Medicines, Ministry of Health, Kampala P.O. Box 7272, Uganda., Morries S; Department of Pharmaceuticals and Natural Medicines, Ministry of Health, Kampala P.O. Box 7272, Uganda., Lawry LL; Overseas Strategic Consulting, Ltd., Philadelphia, PA 19102, USA., Joshi MP; USAID Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, Management Sciences for Health (MSH), Arlington, VA 22203, USA., Stergachis A; School of Pharmacy, University of Washington, Seattle, WA 98105, USA.; Department of Global Health, University of Washington, Seattle, WA 98105, USA., Konduri N; USAID Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, Management Sciences for Health (MSH), Arlington, VA 22203, USA.
Jazyk:	angličtina
Zdroj:	Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2022 Feb 04; Vol. 11 (2). Date of Electronic Publication: 2022 Feb 04.
DOI:	10.3390/antibiotics11020199
Abstrakt:	Standardized monitoring of antibiotic use underpins the effective implementation of antimicrobial stewardship interventions in combatting antimicrobial resistance (AMR). To date, few studies have assessed antibiotic use in hospitals in Uganda to identify gaps that require intervention. This study applied the World Health Organization's standardized point prevalence survey methodology to assess antibiotic use in 13 public and private not-for-profit hospitals across the country. Data for 1077 patients and 1387 prescriptions were collected between December 2020 and April 2021 and analyzed to understand the characteristics of antibiotic use and the prevalence of the types of antibiotics to assess compliance with Uganda Clinical Guidelines; and classify antibiotics according to the WHO Access, Watch, and Reserve classification. This study found that 74% of patients were on one or more antibiotics. Compliance with Uganda Clinical Guidelines was low (30%); Watch-classified antibiotics were used to a high degree (44% of prescriptions), mainly driven by the wide use of ceftriaxone, which was the most frequently used antibiotic (37% of prescriptions). The results of this study identify key areas for the improvement of antimicrobial stewardship in Uganda and are important benchmarks for future evaluations.
Databáze:	MEDLINE
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