Current status on antimicrobial activity of a tricalcium silicate cement.

Autor: Ruiz-Linares M; Department of Stomatology, School of Dentistry, University of Granada., de Oliveira Fagundes J; Department of Stomatology, School of Dentistry, University of Granada., Solana C; Department of Stomatology, School of Dentistry, University of Granada., Baca P; Department of Stomatology, School of Dentistry, University of Granada., Ferrer-Luque CM; Department of Stomatology, School of Dentistry, University of Granada.
Jazyk: angličtina
Zdroj: Journal of oral science [J Oral Sci] 2022 Apr 01; Vol. 64 (2), pp. 113-117. Date of Electronic Publication: 2022 Feb 23.
DOI: 10.2334/josnusd.21-0439
Abstrakt: Biodentine (BD) is a bioactive material with many indications in endodontic therapy. The purpose of this study was to compile and review the outcomes of in vitro and in vivo studies of BD in terms of antimicrobial effectiveness. An electronic search was carried out in PubMed, from January 2009-April 2021 using the keywords: (Biodentine or dentine substitute or "Ca 3 SiO 5 " or tricalcium silicate cement or bioceramic cement) and (antimicrobial activity or antimicrobial effect or antimicrobial effectiveness or antibacterial activity or antibacterial effect or antibacterial effectiveness or antibiofilm activity or antibiofilm effectiveness). Two independent reviewers evaluated the studies for eligibility. All studies that did not include BD or its antimicrobial properties, as well as abstracts not written in English, were excluded. This review identified the need to develop standardized methods to evaluate antimicrobial activity in vitro. Most of the studies were against planktonic bacteria and gave conflicting results. Studies ex vivo and in vivo against biofilm are required to elucidate the antimicrobial activity of BD.
Databáze: MEDLINE