Impact of preoperative staging with contrast-enhanced mammography for localized breast cancer management.

Autor:	Montrognon F; Department of Radiology, University Hospital Center, Rouen, France., Clatot F; Department of Medical Oncology, Henri Becquerel Center, Rouen, France., Berghian A; Department of Anatomopathology, Henri Becquerel Center, Rouen, France., Douvrin F; Department of Radiology, Henri Becquerel Center, Rouen, France., Quieffin F; Department of Radiology, Henri Becquerel Center, Rouen, France., Defta D; Department of Radiology, Henri Becquerel Center, Rouen, France., Buquet A; Department of Radiology, Henri Becquerel Center, Rouen, France., Ferret M; Department of Radiology, Henri Becquerel Center, Rouen, France., Lequesne J; Department of Clinical Research, Henri Becquerel Center, Rouen, France., Leheurteur M; Department of Medical Oncology, Henri Becquerel Center, Rouen, France., Fontanilles M; Department of Medical Oncology, Henri Becquerel Center, Rouen, France., Georgescu D; Department of Gynecology and Breast surgery, Henri Becquerel Center, Rouen, France., Callonnec F; Department of Radiology, Henri Becquerel Center, Rouen, France.
Jazyk:	angličtina
Zdroj:	The British journal of radiology [Br J Radiol] 2022 Jun 01; Vol. 95 (1134), pp. 20210765. Date of Electronic Publication: 2022 Mar 09.
DOI:	10.1259/bjr.20210765
Abstrakt:	Objective: A precise evaluation of the disease extent is mandatory before surgery for early breast cancer (EBC). Contrast-enhanced mammography (CEDM) is a recent technique that may help define adequate surgery. Methods: This retrospective study included consecutive patients referred to a cancer center between November 2016 and July 2017 for biopsy-confirmed invasive EBC management. The primary objective was to evaluate the rate of surgical changes after incorporating the results of the preoperative staging examination, including CEDM. Results: A total of 231 patients were screened for inclusion, and 132 patients were included, corresponding to 134 lesions. The first surgical plan was modified for 33 patients (25%), which represented 34 lesions. For 8 patients (6%), the surgery was cancelled in preference for neoadjuvant chemotherapy; for 16 patients (12.1%), the primary tumor procedure was enlarged; and for 23 patients (17.4%) the lymph node management was modified. Surgery was changed only due to the CEDM results for 24 patients (18.5%) and consisted of a more invasive procedure due to a more extended, multifocal or multicentric lesion than seen on the standard imaging. Anatomopathological surgery piece findings were well correlated with contrast-enhanced mammography results. Overall, there was no increase in the delay between the planned date of surgery and the effective surgical procedure (median 0 days). Conclusion: CEDM added to preoperative staging helped define better surgical management without increasing delay in the surgical procedure. Advances in Knowledge: CEDM is a reliable technique that should be considered as part of preoperative staging for EBC.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu