| Autor: |
Benniston AC; Chemistry-School of Natural & Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE7 1RU, UK. andrew.benniston@ncl.ac.uk., Zeng L; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China. |
| Jazyk: |
angličtina |
| Zdroj: |
Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2022 Mar 15; Vol. 51 (11), pp. 4202-4212. Date of Electronic Publication: 2022 Mar 15. |
| DOI: |
10.1039/d2dt00254j |
| Abstrakt: |
Photorelease complexes represent a class of agents for which UV-visible light triggers the expulsion of a specfic molecule that is intrinsically part of the inner coordination sphere or held in close proximity to the metal centre. The reaction does not occur in the ground-state complex and requires a photon, but an additional agent may be present that facilitates the release process. In this context, the perspective article covers recent papers from the past five years (2017-2021) on metal-based complexes containing ligands that are expelled under light activation. In addition, the examples primarily focus on ligands with potential biological activity and have specfic therapeutic applications. Some examples include NO, CO, Cl - , peptides, pharmacophores and redox-active compounds. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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