| Autor: |
Jia WP; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Kou FY; Human Resources, Chinese PLA General Hospital, Beijing 100853, China., Xu HL; Big Data Center of Chinese PLA General Hospital, Beijing 100853, China., Han K; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Cao WZ; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Wang SS; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Song Y; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Yang SS; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Yan YF; Department of Endocrinology, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Cao F; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Xue WG; Big Data Center of Chinese PLA General Hospital, Beijing 100853, China., Wang YB; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Meng WW; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China., Liu M; Graduate School of Chinese PLA General Hospital, Beijing 100853, China., He Y; Institute of Geriatrics, State Key Geriatric Disease Research Center, Beijing Key Laboratory of Aging and Geriatrics, the Second Clinical Center, Chinese PLA General Hospital, Beijing 100853, China. |
| Abstrakt: |
Objective: To explore the distribution patterns of cardiometabolic diseases (CMD) in elderly patients with colorectal cancer, and provide a reference for the prevention and treatment of cardiovascular metabolic diseases in these patients. Methods: Clinical data of 3 894 elderly patients with colorectal cancer from January 2008 to March 2018 admitted in the Chinese PLA General Hospital were recruited and the incidence rate of CMD was retrospectively analyzed. The influence factors of elderly patients with colorectal cancer combined with CMD were analyzed by multivariate Logistic regression model. Results: The morbidity rate of CMD in elderly patients with colorectal cancer is 33.4% (1 301/3 894), among them, the morbidity rate of the male was 31.9% (768/2 409), and that of the female was 35.9% (533/1 485). There was not significant difference between these two sex ( P =0.074). The morbidity rates of CMD in patients of 65-74 years, 75-84 years and ≥85 years were 30.6% (754/2 462), 37.0% (479/1 294) and 49.3% (68/138), respectively, with significant differences ( P <0.001). Multiple Logistic regression analysis revealed that female ( OR =1.213, 95% CI: 1.056-1.394), age (75-84 years group: OR =1.344, 95% CI: 1.164-1.552; ≥85 years group: OR =2.345, 95% CI: 1.651-3.331) and body mass index (BMI 18.5-24.9 kg/m(2) group: OR =1.319, 95% CI: 1.065-1.638; ≥25 kg/m(2) group: OR =2.041, 95% CI: 1.627-2.561) were independent risk factors for elderly colorectal cancer patients with CMD. Conclusion: The morbidity rate of CMD in elderly patients with colorectal cancer increases with age and it is urgent to strengthen multidisciplinary cooperation and develop reasonable treatment plans to extend the survival and life quality of these patients. |
