Does omalizumab use in chronic spontaneous urticaria results in improvement in sexual functions?

Autor: Durmaz K; Clinic of Dermatology, Bozuyuk State Hospital, Bilecik, Turkey., Ataseven A; Department of Dermatology, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey., Temiz SA; Clinic of Dermatology, Eregli State Hospital, Konya, Turkey., Isik B; Department of Dermatology, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey., Dursun R; Department of Dermatology, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
Jazyk: angličtina
Zdroj: Journal of cosmetic dermatology [J Cosmet Dermatol] 2022 Oct; Vol. 21 (10), pp. 4877-4881. Date of Electronic Publication: 2022 Feb 28.
DOI: 10.1111/jocd.14872
Abstrakt: Background: Chronic spontaneous urticaria (CSU) is a disease that can affect the patient's quality of life (QoL), sexual functions, and mood.
Objective: We planned a retrospective study to investigate the effects of omalizumab use in CSU patients on sexual function. We also aimed to evaluate the sexual function, quality of life (QoL), and mood of CSU patients compared to the control group consisting of idiopathic pruritus patients.
Methods: A review of patients' records with CSU attending the dermatology outpatient clinic from January 2020 to June 2020 was done. Urticaria activation score (UAS7), Beck depression inventory (BDI), Dermatology life quality index (DLQI), female sexual function index (FSFI) to female participants, and the international index of erectile function (IIEF) to male participants were used to assess the impact of the disease on patients' life. The obtained data were analyzed by using SPSS software.
Results: Each one of the mean UAS, BDI, and DLQI score values decreased significantly in weeks in omalizumab group patients. IIEF score in male patients and FSFI score in female patients also increased in weeks in omalizumab group patients.
Conclusions: Omalizumab can play an effective role in enhancing the sexual function of CSU patients in addition to improving their DLQI.
(© 2022 Wiley Periodicals LLC.)
Databáze: MEDLINE
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