No acetyl-CoA keeps Plasmodium at bay.
| Autor: | Jeffers V; Department of Molecular, Cellular and Biomedical Life Sciences, University of New Hampshire, Durham NH 03824, USA. Electronic address: victoria.jeffers@unh.edu., Child MA; Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. Electronic address: m.child@imperial.ac.uk. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cell chemical biology [Cell Chem Biol] 2022 Feb 17; Vol. 29 (2), pp. 174-176. |
| DOI: | 10.1016/j.chembiol.2022.02.003 |
| Abstrakt: | Acetyl-coenzyme A is an important metabolite and regulates diverse cellular processes, including metabolism and epigenetics. In this issue of Cell Chemical Biology, Summers et al. (2022) describe an essential parasite enzyme, acetyl-coenzyme A synthetase, as a target of two antimalarial small molecules active against liver and blood stages of the parasite. (Copyright © 2022 Elsevier Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|