Marijuana in Orthopaedics: Effects on Bone Health, Wound-Healing, Surgical Complications, and Pain Management.
| Autor: | Heath DM; Department of Orthopaedics, UT Health San Antonio, San Antonio, Texas., Koslosky EJ; Department of Orthopaedics, UT Health San Antonio, San Antonio, Texas., Bartush KC; Department of Orthopaedics, UT Health San Antonio, San Antonio, Texas., Hogue GD; Department of Orthopaedics, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts. |
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| Jazyk: | angličtina |
| Zdroj: | JBJS reviews [JBJS Rev] 2022 Feb 21; Vol. 10 (2). Date of Electronic Publication: 2022 Feb 21. |
| DOI: | e21.00184 |
| Abstrakt: | »: Marijuana use is on the rise in the United States, and there is a paucity of information on the effects of cannabis and its chemical constituents on bone health, wound-healing, surgical complications, and pain management. »: Current evidence suggests that cannabidiol (CBD) may enhance bone health and metabolism, while Δ9-tetrahydrocannabinol (Δ9-THC), the major psychoactive component in marijuana, has an inhibitory effect. »: Marijuana users are at higher risk for delayed bone-healing, demonstrate lower bone mineral density, are at increased risk for fracture, and may experience postoperative complications such as increased opioid use and hyperemesis. Competing Interests: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSREV/A810). (Copyright © 2022 by The Journal of Bone and Joint Surgery, Incorporated.) |
| Databáze: | MEDLINE |
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