| Autor: |
Lines AM; Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Bello JM; Spectra Solutions, Inc., Norwood, Massachusetts 02062, United States., Gasbarro C; Spectra Solutions, Inc., Norwood, Massachusetts 02062, United States., Bryan SA; Pacific Northwest National Laboratory, Richland, Washington 99354, United States. |
| Jazyk: |
angličtina |
| Zdroj: |
Analytical chemistry [Anal Chem] 2022 Mar 01; Vol. 94 (8), pp. 3652-3660. Date of Electronic Publication: 2022 Feb 16. |
| DOI: |
10.1021/acs.analchem.1c05228 |
| Abstrakt: |
Real-time and in situ process monitoring is a powerful tool that can empower operators of hazardous processes to better understand and control their chemical systems without increased risk to themselves. However, the application of monitoring techniques to complex chemical processes can face challenges. An example of this is the application of optical spectroscopy, otherwise capable of providing detailed chemical composition information, to processes exhibiting variable turbidity. Here, details on a novel combined Raman spectroscopy and turbidimetry probe are discussed, which advances current technology to enable flexible and robust in situ monitoring of a flowing process stream. Furthermore, the analytical approach to accurately account for both Raman signal and turbidity while quantifying chemical targets is detailed. This new approach allows for accurate analysis without requiring assumptions of stable process chemistry, which may be unlikely in applications such as waste cleanup. Through leveraging Raman and turbidity data simultaneously collected from the combined probe within chemometric models, accurate quantification of multiple chemical targets can be achieved under conditions of variable concentrations and turbidity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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