Striatal dominant lupus encephalitis-Is it vasculitis or an autoimmune process? Literature review & new case report with vessel wall imaging.

Autor:	Raventhiranathan N; Department of Radiology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210., Hussien AR; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX., Mirchia K; Department of Radiology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210., Swarnkar A; Department of Radiology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210., Mangla R; Department of Radiology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210.
Jazyk:	angličtina
Zdroj:	Radiology case reports [Radiol Case Rep] 2022 Feb 04; Vol. 17 (4), pp. 1205-1210. Date of Electronic Publication: 2022 Feb 04 (Print Publication: 2022).
DOI:	10.1016/j.radcr.2022.01.002
Abstrakt:	Neurological and psychiatric symptoms are highly prevalent in the initial manifestation of systemic lupus erythematosus (SLE) and is classified as neuropsychiatric systemic lupus erythematosus (NPSLE). Despite the high prevalence rate of this condition, it is still very poorly understood and often delayed in its diagnosis due to its variety in clinical manifestations. For our case, an eighteen-year-old male who was recently diagnosed with SLE presented with progressive confusion, visual and auditory hallucinations, in addition to high fevers, diarrhea, abdominal and flank pain. Upon initial presentation, he was treated for sepsis while trying to identify a source of infection. However, with the help of laboratory tests like CSF analysis and autoantibody serum studies as well as neuroradiologic imaging, we were able to rule out infectious causes and diagnose our patient with lupus induced striatal encephalitis. We present the first case of striatal encephalitis with vessel wall imaging to ultimately rule out lupus associated vasculitis. The importance of MRI imaging and identification of specific patterns associated with autoimmune encephalitis allowed rapid diagnosis and initiated immediate treatment in the hopes of reducing long term affects from neuroinflammation in our young patient. (© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu