| Autor: |
Peavy DL, Fairchild EJ 2nd |
| Jazyk: |
angličtina |
| Zdroj: |
Infection and immunity [Infect Immun] 1986 May; Vol. 52 (2), pp. 613-6. |
| DOI: |
10.1128/iai.52.2.613-616.1986 |
| Abstrakt: |
Ethane has been identified and quantitated in air exhaled by mice following intraperitoneal injection of 20, 40, or 200 mg of Escherichia coli O111:B4 lipopolysaccharide (LPS) per kg. Significant increases in ethane concentration occurred within 1 to 5 h after LPS administration. In addition, increased concentrations of malondialdehyde were found in crude homogenates of livers obtained from mice 16 h after administration of 20 mg of LPS per kg. These results suggest that lipid peroxidation may be an important mechanism responsible for LPS toxicity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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