[Primary diffuse meningeal melanomatosis: a literature review and a case report].

Autor:	Sitovskaya DA; Prof. A.L. Polenov Russian Research Institute of Neurosurgery - Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia, St. Petersburg, Russia.; City Mariinskaya Hospital, St. Petersburg, Russia., Verbitsky OP; City Mariinskaya Hospital, St. Petersburg, Russia., Petrova YA; City Mariinskaya Hospital, St. Petersburg, Russia., Sokolova TV; Prof. A.L. Polenov Russian Research Institute of Neurosurgery - Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia, St. Petersburg, Russia., Zabrodskaya YM; Prof. A.L. Polenov Russian Research Institute of Neurosurgery - Branch V.A. Almazov National Medical Research Center of the Ministry of Health of Russia, St. Petersburg, Russia.
Jazyk:	ruština
Zdroj:	Arkhiv patologii [Arkh Patol] 2022; Vol. 84 (1), pp. 27-32.
DOI:	10.17116/patol20228401127
Abstrakt:	Primary melanocytic tumors of the central nervous system (CNS) are extremely rare and account for only 1% of all melanomas and 0.05% of primary brain tumors. In case of diffusely invasive lesions of the pia mater with a tumor of melanocytic origin (without signs of extracranial metastases), the tumors are classified as primary diffuse meningeal melanomatosis (PDMM). The latter is an extremely rare subtype of CNS malignant tumor with an incidence rate of 1 in 20 million people. Despite the development of neuroimaging techniques, today a morphological examination remains the main and most accurate method for verifying CNS melanocytic tumors. The paper describes a fatal case of PMMD manifested as epileptic syndrome, with a rapidly progressive course.
Databáze:	MEDLINE
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