Acanthamoeba Keratitis: A Single-Institution Series of Four Cases With Literature Review.
| Autor: | Smith C; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, USA., Ashraf N; Department of Internal Medicine, Division of Infectious Diseases, University of Kansas Medical Center, Kansas City, USA., Haghnegahdar M; Department of Ophthalmology, University of Kansas Medical Center, Kansas City, USA., Goins K; Department of Ophthalmology, University of Kansas Medical Center, Kansas City, USA., Newman JR; Department of Internal Medicine, Division of Infectious Diseases, University of Kansas Medical Center, Kansas City, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Jan 11; Vol. 14 (1), pp. e21112. Date of Electronic Publication: 2022 Jan 11 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.21112 |
| Abstrakt: | Acanthamoeba species are free-living protozoa found pervasively in water and soil, which can cause infections of the central nervous system, skin, and eye. Amoebic keratitis (AK) is a vision-threatening, often chronic infection that is associated with the use of soft contact lenses due to corneal microtrauma and improper cleaning and storage. Although AK infections are rare, they cause significant morbidity including vision loss due to the diagnostic and therapeutic challenges they pose. The clinical course is determined by the organism's inherent pathogenicity, delay of diagnosis, and the paucity of data on effective therapeutic regimens. The case series and review of literature that follows examine current latest best practices in AK diagnosis including in vivo confocal microscopy (IVCM) and therapeutic interventions including miltefosine. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Smith et al.) |
| Databáze: | MEDLINE |
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