[Assessment of the impact of pharmaceutical consultations at initiation of a treatment with emicizumab in patients with severe hemophilia A without inhibitors].

Autor:	Nasr Allah M; Pharmacie à usage intérieur, hôpital Cochin, Assistance publique-Hôpitaux de Paris, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France., Pieragostini R; Pharmacie à usage intérieur, hôpital Cochin, Assistance publique-Hôpitaux de Paris, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France. Electronic address: remi.pieragostini@aphp.fr., Oka G; Pharmacie à usage intérieur, hôpital Cochin, Assistance publique-Hôpitaux de Paris, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France., Batista R; Pharmacie à usage intérieur, hôpital Cochin, Assistance publique-Hôpitaux de Paris, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France., Stieltjes N; Centre d'accueil et de traitement des hémophiles-hémostase-thrombose, hôpital Cochin, Assistance publique-Hôpitaux de Paris, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France., Lopez I; Pharmacie à usage intérieur, hôpital Cochin, Assistance publique-Hôpitaux de Paris, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France.
Jazyk:	francouzština
Zdroj:	Annales pharmaceutiques francaises [Ann Pharm Fr] 2022 Nov; Vol. 80 (6), pp. 915-922. Date of Electronic Publication: 2022 Feb 10.
DOI:	10.1016/j.pharma.2022.02.003
Abstrakt:	Since 2019, severe haemophilia A without inhibitors can be treated with emicizumab. Its action, route of administration and management justified the creation of new tools for therapeutic education sessions addressed to patients. The main objective of our work was to assess the knowledge and skills acquired by patients after therapeutic education. The various documents created were a video, a slideshow, clinical cases in form of cards, and summary sheets intended for patients. At treatment beginning, a pharmaceutical consultation was proposed to all patients. Two months later, an evaluation was carried out and a second pharmaceutical consultation aimed to consolidate the achievements of patients. Simultaneously, a clinical self-evaluation by the patients was carried out. Thirty-six patients were included in the study. Theoretical items: method of manufacture, mechanism of action and regimen, are known for more than ¾ of patients. Practical skills, such as administration modalities, management of missed doses or bleeding, are familiar for more than 8 out of 10 patients. Sixteen (44.4%) patients presented an up-to-date haemophilia card. The assessment of the knowledge and skills of patients is encouraging since most of the items are acquired. These result highlights the interest of the new tools developed for the therapeutic education sessions. (Copyright © 2022 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.)
Databáze:	MEDLINE
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