Long-term experience with timolol ophthalmic solution in patients with open-angle glaucoma.

Autor: Boger WP 3rd, Puliafito CA, Steinert RF, Langston DP
Jazyk: angličtina
Zdroj: Ophthalmology [Ophthalmology] 1978 Mar; Vol. 85 (3), pp. 259-67.
DOI: 10.1016/s0161-6420(78)35673-6
Abstrakt: Timolol was used by 37 glaucoma patients from 1 to 18 months. Of those 37 patients, 31 used timolol for three months or longer and 7 used timolol for over one year. Timolol produced sustained reductions in intraocular pressure with continuous administration and did not induce miosis, accommodative spasm, or other annoying side effects. Systemic absorption produced a mild slowing of resting pulse rate. In some patients, timolol's ocular hypotensive effects are additive to miotics and carbonic anhydrase inhibitors.
Databáze: MEDLINE