Outcomes of hospitalizations with acute respiratory distress syndrome with and without atrial fibrillation - Analyses from the National Inpatient Sample (2004-2014).

Autor: Jamal S; Department of Internal Medicine, Central Michigan University, Mount Pleasant, MI, USA. Electronic address: Jamal1sm@cmich.edu., Ijaz SH; Division of Cardiovascular Medicine, Lahey Hospital and Medical Center, Burlington, MA, USA., Minhas AMK; Department of Internal Medicine, Forrest General Hospital, Hattiesburg, Mississippi, USA., Kichloo A; Department of Internal Medicine, Central Michigan University, Mount Pleasant, MI, USA. Electronic address: kichlooasim@gmail.com., Khan MZ; Department of Internal Medicine, West Virginia University, Morgantown, WV, USA., Albosta M; Department of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL, USA. Electronic address: albos1ms@cmich.edu., Aljadah M; Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Banga S; Division of Cardiovascular Medicine, Michigan State University, East Lansing, MI, USA., Baloch ZQ; Division of Cardiovascular Medicine, Michigan State University, East Lansing, MI, USA., Aboud H; Department of Internal Medicine, Central Michigan University, Mount Pleasant, MI, USA., Haji AQ; Division of Cardiovascular Medicine, Martinsburg VA Medical Center, West Virginia, USA., Sheikh A; Division of Cardiovascular Medicine, Michigan State University, East Lansing, MI, USA. Electronic address: ali.sheikh@sparrow.org., Kanjwal K; Division of Cardiovascular Medicine, McLaren Greater Lansing, East Lansing, MI, USA.
Jazyk: angličtina
Zdroj: The American journal of the medical sciences [Am J Med Sci] 2022 Sep; Vol. 364 (3), pp. 289-295. Date of Electronic Publication: 2022 Feb 06.
DOI: 10.1016/j.amjms.2022.01.020
Abstrakt: Background: Acute respiratory distress syndrome (ARDS) is associated with high mortality. Atrial fibrillation (AF) is a common arrhythmia seen in critically ill patients. The impact of AF on the outcomes in patients with ARDS is less understood. In this analysis we attempt to evaluate the association of concurrent AF and various clinical outcomes in patients with ARDS.
Methods: We conducted a retrospective analysis of adult discharges from the National Inpatient Sample (NIS) between 2004 and 2014. International Classification of Disease codes were used to identify those with ARDS and AF.
Results: We found 1,200,737 hospitalizations with ARDS, out of which 238,455 had concomitant diagnosis of AF. Hospitalizations with AF had higher prevalence of comorbidities including chronic pulmonary disease, diabetes mellitus, hypertension, obesity, congestive heart failure and renal failure. On adjusted analysis, AF was associated with increased odds of acute myocardial infarction, cardiogenic shock, pressor use, acute kidney injury, permanent pacemaker implantation, cardiac arrest, mechanical circulatory support use and higher length of stay and inflation-adjusted cost in hospitalizations with ARDS. However, there was no significant difference in adjusted all-cause mortality in ARDS with and without AF (25.42% vs 20.23%, p=0.53).
Conclusions: AF is associated with worse clinical outcomes, higher length of stay and cost in ARDS hospitalizations as compared to those without AF.
Competing Interests: Declaration of Competing Interest None declared.
(Copyright © 2022. Published by Elsevier Inc.)
Databáze: MEDLINE