Residual concentrations of antimicrobial growth promoters in poultry litter favour plasmid conjugation among Escherichia coli.

Autor: Saraiva MMS; Department of Animal Science, Center for Agricultural Sciences, Federal University of Paraiba (CCA/UFPB), Areia, PB, Brazil.; Department of Pathology, Theriogenology and One Health, Laboratory of Ornithopathology, São Paulo State University (FCAV/Unesp), Jaboticabal, SP, Brazil., Silva NMV; Department of Animal Science, Center for Agricultural Sciences, Federal University of Paraiba (CCA/UFPB), Areia, PB, Brazil.; Instituto Federal do Sertão Pernambucano - Campus Petrolina, Petrolina, Brazil., Ferreira VA; Department of Pathology, Theriogenology and One Health, Laboratory of Ornithopathology, São Paulo State University (FCAV/Unesp), Jaboticabal, SP, Brazil., Moreira Filho ALB; Department of Animal Science, Center for Human, Social and Agricultural Sciences, Federal University of Paraiba (CCHSA/UFPB), Bananeiras, PB, Brazil., Givisiez PEN; Department of Animal Science, Center for Agricultural Sciences, Federal University of Paraiba (CCA/UFPB), Areia, PB, Brazil., Freitas Neto OC; Department of Preventive Veterinary Medicine, Veterinary School, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG, Brazil., Berchieri Júnior A; Department of Pathology, Theriogenology and One Health, Laboratory of Ornithopathology, São Paulo State University (FCAV/Unesp), Jaboticabal, SP, Brazil., Gebreyes WA; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.; Global One Health Initiative (GOHi), The Ohio State University, Columbus, OH, USA., de Oliveira CJB; Department of Animal Science, Center for Agricultural Sciences, Federal University of Paraiba (CCA/UFPB), Areia, PB, Brazil.; Global One Health Initiative (GOHi), The Ohio State University, Columbus, OH, USA.
Jazyk: angličtina
Zdroj: Letters in applied microbiology [Lett Appl Microbiol] 2022 May; Vol. 74 (5), pp. 831-838. Date of Electronic Publication: 2022 Feb 21.
DOI: 10.1111/lam.13671
Abstrakt: Considering that plasmid conjugation is a major driver for the dissemination of antimicrobial resistance in bacteria, this study aimed to investigate the effects of residual concentrations of antimicrobial growth promoters (AGPs) in poultry litter on the frequencies of IncFII-FIB plasmid conjugation among Escherichia coli organisms. A 2 × 5 factorial trial was performed in vitro, using two types of litter materials (sugarcane bagasse and wood shavings) and five treatments of litter: non-treated (CON), herbal alkaloid sanguinarine (SANG), AGPs monensin (MON), lincomycin (LCM) and virginiamycin (VIR). E. coli H2332 and E. coli J62 were used as donor and recipient strains, respectively. The presence of residues of monensin, lincomycin and virginiamycin increased the frequency of plasmid conjugation among E. coli in both types of litter materials. On the contrary, sanguinarine significantly reduced the frequency of conjugation among E. coli in sugarcane bagasse litter. The conjugation frequencies were significantly higher in wood shavings compared with sugarcane bagasse only in the presence of AGPs. Considering that the presence of AGPs in the litter can increase the conjugation of IncFII-FIB plasmids carrying antimicrobial resistance genes, the real impact of this phenomenon on the dissemination of antimicrobial resistant bacteria in the poultry production chain must be investigated.
(© 2022 Society for Applied Microbiology.)
Databáze: MEDLINE
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