| Autor: |
Artem'ev GA; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Rusinov VL; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Kopchuk DS; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Savchuk MI; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Santra S; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Ulomsky EN; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Zyryanov GV; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Majee A; Department of Chemistry; Visva-Bharati (A Central University), Santiniketan 731235, India., Du W; Department of Pharmacology (State-Province Key Laboratories of Biomedicine Pharmaceutics of China, Key Laboratory of Cardiovascular research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Charushin VN; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com., Chupakhin ОN; I. Ya. Postovskiy Institute of Organic Synthesis, UB of the RAS, 22 S. Kovalevskoy Str., Yekaterinburg, 620219, Russian Federation.; Ural Federal University, 19 Mira str., Yekaterinburg, 620002, Russian Federation. sougatasantra85@gmail.com. |
| Abstrakt: |
Fragments of 1,2,4-triazolo[5,1- c ][1,2,4]triazin-7-one are found in many compounds with various types of biological activities, including the antiviral drug Riamilovir (Triazavirin®), which shows activity against SARS-CoV-2 (COVID-19). Therefore, the development of convenient methods for the synthesis of new derivatives of 1,2,4-triazolo[5,1- c ][1,2,4]triazin-7-one is always in demand. This review systematizes the information on the most common synthetic methods for constructing the 1,2,4-triazolo[5,1- c ][1,2,4]triazin-7-one heterocyclic system. |
