Magnetic resonance imaging findings associated with recurrence in idiopathic granulomatous mastitis.

Autor: Kayadibi Y; Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Radiology, Kocamustafapasa, Istanbul, Turkey. Electronic address: yasemin.kayadibi@iuc.tr., Ucar N; Gaziosmanspasa Education and Research Hospital, Department of Radiology, Gaziosmanpasa, Istanbul, Turkey., Akan YN; Gaziosmanspasa Education and Research Hospital, Department of Radiology, Gaziosmanpasa, Istanbul, Turkey., Kaya MF; Gaziosmanspasa Education and Research Hospital, Department of Radiology, Gaziosmanpasa, Istanbul, Turkey., Yildirim E; Gaziosmanspasa Education and Research Hospital, Department of General Surgery, Gaziosmanpasa, Istanbul, Turkey., Kurt SA; Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Radiology, Kocamustafapasa, Istanbul, Turkey., Boy FNS; Fatih Sultan Mehmet Education and Research Hospital, Department of Radiology, Atasehir, Istanbul, Turkey., Taskin F; Acibadem Mehmet Ali Aydinlar University, Senology Research Institute Maslak, İstanbul, Turkey., Icten GE; Acibadem Mehmet Ali Aydinlar University, Senology Research Institute Maslak, İstanbul, Turkey.
Jazyk: angličtina
Zdroj: Clinical imaging [Clin Imaging] 2022 Apr; Vol. 84, pp. 47-53. Date of Electronic Publication: 2022 Feb 03.
DOI: 10.1016/j.clinimag.2022.01.010
Abstrakt: Purpose: To evaluate magnetic resonance imaging (MRI) findings related to recurrence of idiopathic granulomatous mastitis (IGM).
Methods: Demographic data [age, number of births, duration of lactation period, body mass index (BMI) and presence of recurrence] of 71 patients who were diagnosed with IGM were analyzed retrospectively. Characteristics of IGM (maximum width, location, involvement of the retroareolar region, deep tissue, skin), fibroglandular density (FGD), background parenchymal enhancement (BPE), distribution and pattern of contrast enhancement, presence of prepectoral edema, abscesses, fistulae, axillary lymphadenopathies on MRI and apparent diffusion coefficient (ADC) values from the pathological area were recorded.
Results: The recurrence rate in patients was 59% (42/71). We found a statistically significant relationship between recurrence and BPE (p = 0.028) and mean ADC (p = 0.035) values (for the cut-off of 1.00 × 10 -3  mm 2 /s; sensitivity = 61.9%, specificity = 69%, AUC = 0.648). However, patients' age (p = 0.346), lactation period (p = 0.470), number of births (p = 0.774), BMI (p = 0.630) maximum width of the area of enhancement (p = 0.112), involvement of the retroareolar region (p = 0.290), deep tissue (p = 0.285), skin (p = 0.230), distribution (p = 0.857) and enhancement pattern (p = 0.157), presence of prepectoral edema (p = 0.094), abscesses (p = 0.441), fistulae (p = 0.809), lymphadenopathies (p = 0.571), and FGT (p = 0.098) were not significantly associated with recurrence.
Conclusion: Our results revealed that recurrent IGM patients showed high BPE and lower mean ADC values. We think that high BPE and low mean ADC (<1.00 × 10 -3  mm 2 /s) on MRI at the diagnosis stage may be a sign of possible future recurrence, and it will be beneficial to follow the patients more closely and arrange the treatment algorithms accordingly.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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