Patients with moderate to severe COVID-19 have an impaired cytokine response with an exhausted and senescent immune phenotype.

Autor: Dhanda AD; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: ashwin.dhanda@plymouth.ac.uk., Felmlee D; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: daniel.felmlee@plymouth.ac.uk., Boeira P; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: paula.boeira@plymouth.ac.uk., Moodley P; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: p.moodley@nhs.net., Tan H; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: huey.tan@plymouth.ac.uk., Scalioni LP; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK., Lilly K; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: kristenlilly@nhs.net., Sheridan DA; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: david.sheridan@plymouth.ac.uk., Cramp ME; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK; Hepatology Research Group, Faculty of Health, University of Plymouth, Plymouth, UK. Electronic address: matthew.cramp@nhs.net.
Jazyk: angličtina
Zdroj: Immunobiology [Immunobiology] 2022 Mar; Vol. 227 (2), pp. 152185. Date of Electronic Publication: 2022 Feb 04.
DOI: 10.1016/j.imbio.2022.152185
Databáze: MEDLINE