Corneal scarring following collagen cross-linking: evidence of increased lysyl oxidase activity.

Autor: Shah SG; Cornea, Cataract & Refractive Surgery Services, Eye Life, Mumbai - 52, India., Shetty R; Cornea & Refractive Surgery Services, Narayana Nethralaya, Bengaluru, India., Ghosh A; GROW Research Laboratory, Narayana Nethralaya Foundation, Bengaluru, India., Shah GY; Vitreo- Retina Services, Eye Life, Mumbai, India.
Jazyk: angličtina
Zdroj: European journal of ophthalmology [Eur J Ophthalmol] 2023 May; Vol. 33 (3), pp. NP23-NP26. Date of Electronic Publication: 2022 Feb 07.
DOI: 10.1177/11206721221078152
Abstrakt: Purpose: To report a case of corneal scarring following collagen cross linking in a young female.
Methods: A 24-year-old female presented to us with complaints of decreased vision and a white spot in her left eye following collagen cross linking (CXL) performed elsewhere, four years prior. We diagnosed her as a case of left eye leucomatous corneal opacity for which she underwent optical penetrating keratoplasty under local anaesthesia. The excised corneal tissue was evaluated by routine histopathology and immunohistochemistry.
Results: At the final follow up visit, one year following corneal transplantation, her visual acuity improved to 20/20, J1 with a clear graft.
Conclusion: Vision threatening corneal scarring may be rarely noted following CXL.
Databáze: MEDLINE