Cutaneous manifestations of COVID-19 in a tertiary COVID-19 referral hospital in the Philippines.

Autor:	Tan CC; Department of Dermatology, University of the Philippines - Philippine General Hospital, Manila, Philippines., Dofitas BL; Department of Dermatology, University of the Philippines - Philippine General Hospital, Manila, Philippines., Frez MLF; Department of Dermatology, University of the Philippines - Philippine General Hospital, Manila, Philippines., Yap CDD; Department of Internal Medicine, University of the Philippines - Philippine General Hospital, Manila, Philippines., Uy JKK; Department of Pediatrics, University of the Philippines - Philippine General Hospital, Manila, Philippines., Ciriaco-Tan CP; Department of Dermatology, University of the Philippines - Philippine General Hospital, Manila, Philippines.
Jazyk:	angličtina
Zdroj:	JAAD international [JAAD Int] 2022 Jun; Vol. 7, pp. 44-51. Date of Electronic Publication: 2022 Feb 02.
DOI:	10.1016/j.jdin.2022.01.007
Abstrakt:	Background: Reports on COVID-19 skin manifestations and associated clinical outcomes are limited. Like viral diseases, cutaneous findings may be present and can help in confirmation and prognostication among those suspected or diagnosed with COVID-19. Objective: To determine COVID-19 cutaneous manifestations and their association with disease severity and course. Methods: This study was conducted in a designated COVID-19 referral hospital from January 1 to March 31, 2021. Skin manifestations recorded from January 1 to February 17 were retrospectively gathered. Reports from February 18 to March 31 were prospectively collected using a dermatologic checklist which was incorporated into all official medical records. Results: A total of 507 confirmed patients with COVID-19 were included. COVID-19 skin signs were detected in 39 patients (7.7%). Morbilliform lesions were most common. Skin signs were significantly associated with severe or critical cases (odds ratio, 3.4; 95% CI, 1.3-8.7) and mortality (relative risk, 2.9; 95% CI, 2.0-4.2). Limitations: Underestimation of prevalence of COVID-19 skin signs due to exclusion of outpatient and discharged patients and the subjective assessment in the retrospective part. Conclusion: Cutaneous signs were significantly associated with severe/critical COVID-19 as well as death among 507 hospitalized patients in a Philippine COVID-19 referral hospital. Competing Interests: None disclosed. (© 2022 by the American Academy of Dermatology, Inc. Published by Elsevier Inc.)
Databáze:	MEDLINE
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