Serum level of Vitamin D is associated with COVID-19 mortality rate in hospitalized patients.

Autor:	Ranjbar M; Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran., Karbalaie Niya MH; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Roham M; Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.; Antimicrobial Resistant Research Center, Iran University of Medical Sciences, Tehran, Iran., Rezaie N; Department of Pulmonology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Yadollahzadeh M; Department of Internal Medicine, School of Medicine, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Farrokhpour M; Department of Internal Medicine, School of Medicine, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Azimi M; Department of Internal Medicine, School of Medicine, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Motamed N; Department of Social Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran., Perumal D; Drug Discovery, Delivery and Patient Care (DDDPC) Theme, School of Life Sciences Pharmacy and Chemistry, Kingston University, London, United Kingdom., Tameshkel FS; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Dadras F; Department of Nephrology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Madani NH; Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran., Ghanbari B; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Faraji A; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Nikkhah M; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Rahmani S; Department of Nephrology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Golgiri F; Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran., Emadi SY; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Abbasi R; Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran., Mohseni I; Department of Interventional Radiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Babaei MR; Department of Interventional Radiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Eskandari R; Department of Cardiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Ataee M; Department of Interventional Radiology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Panahi M; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Zamani F; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Makiani MJ; Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.; Antimicrobial Resistant Research Center, Iran University of Medical Sciences, Tehran, Iran., Laali A; Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.; Antimicrobial Resistant Research Center, Iran University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences [J Res Med Sci] 2021 Nov 29; Vol. 26, pp. 112. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
DOI:	10.4103/jrms.JRMS_1151_20
Abstrakt:	Background: Due to widespread of coronavirus disease 2019 (COVID-19) infection, identification of its risk factors and clinical characteristics are important. The aim of the present study was to assess Vitamin D levels in individuals with severe acute respiratory syndrome coronavirus-19 infection and to report on its potential as a predictive marker. Materials and Methods: All patients, diagnosed with COVID-19 infection from February 16 to March 21, 2020, and referred to Firoozgar Hospital, Tehran, Iran, were enrolled in this study. Vitamin D analysis was undertaken on patient serum samples using a commercial kit (Pars Azmoon Co., Tehran, Iran). SPSS v. 22 was used for statistical analysis. Results: Vitamin D serum concentration was analyzed in a total of 317 patients whose mean age ± standard deviation was 62.05 ± 15 years and with 62.5% being male. A significant association of Vitamin D level and death was observed. Higher levels of serum Vitamin D had protection against death (odds ratio = 0.955 [95% confidence interval = 0.923-0.988], P = 0.008). Conclusion: As a preliminary study in the Iranian population who suffered COVID-19 disease, we identified that Vitamin D deficiency was associated with a higher death rate and intensive care unit admission. Competing Interests: There are no conflicts of interest. (Copyright: © 2021 Journal of Research in Medical Sciences.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu PDF