Dialectical behavior therapy skills training for individuals with multiple sclerosis and their support partners: A pilot randomized controlled trial.

Autor: Hughes AJ; Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Address: 600N Wolfe St, Phipps Rm 174, Baltimore, MD 21287, USA. Electronic address: abbeyjhughes@jhmi.edu., Botanov Y; Department of Psychology, Pennsylvania State University - York, Address: 1031 Edgecomb Ave, Grumbacher ISTC Room 220, York, PA 17403, USA., Beier M; Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Address: 600N Wolfe St, Phipps Rm 174, Baltimore, MD 21287, USA.
Jazyk: angličtina
Zdroj: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2022 Mar; Vol. 59, pp. 103481. Date of Electronic Publication: 2022 Jan 08.
DOI: 10.1016/j.msard.2021.103481
Abstrakt: Background: Symptoms of anxiety, depression, and emotion dysregulation are common among individuals with MS and their support partners. Dialectical behavior therapy (DBT) - a type of cognitive behavioral intervention - may be a promising treatment for individuals affected by MS. This pilot randomized controlled trial (RCT) assessed the effects and feasibility of remotely delivered DBT skills on anxiety and depression symptoms and emotion dysregulation in individuals with MS and their support partners.
Methods: This study featured a single-masked, two-arm, parallel group design. Twenty pairs of individuals with MS and their support partners (n = 40) were randomized to 12 weeks of DBT or facilitated peer support (FPS). Masked assessments were completed at weeks 0 (baseline), 13 (post-intervention), and 26 (follow-up).
Results: At post-intervention (primary endpoint), participants randomized to DBT exhibited significantly greater reductions in anxiety and depression symptoms compared to FPS (B = 4.45, p = .04, Cohen's d = 0.57). Secondary outcomes of emotion dysregulation and well-being favored the DBT group but did not reach statistical significance (ds = 0.51, ps = 0.07). Effects were not maintained at follow-up. Most (86%) individuals screened were eligible for the trial, and retention (70%) did not differ between study arms.
Conclusions: This pilot RCT provides encouraging evidence that DBT skills is feasible and may improve depression, anxiety, and emotion dysregulation for individuals with MS and their support partners. Future research is needed to optimize maintenance of DBT skills, investigate mechanisms for these improvements, and replicate these promising effects in a fully powered trial.
(Copyright © 2022. Published by Elsevier B.V.)
Databáze: MEDLINE
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