Candida glabrata chorioamnionitis in a twin pregnancy following in vitro fertilisation: a rare cause of septic miscarriage.
| Autor: | Yusoff MA; Obstetrics and Gynaecology, Singapore General Hospital, Singapore mdashrafyusoff@gmail.com., Wee ILE; Infectious Diseases, Singapore General Hospital, Singapore., Sim JXY; Infectious Diseases, Singapore General Hospital, Singapore., Yang L; Obstetrics and Gynaecology, Singapore General Hospital, Singapore. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2022 Feb 03; Vol. 15 (2). Date of Electronic Publication: 2022 Feb 03. |
| DOI: | 10.1136/bcr-2021-246629 |
| Abstrakt: | Candida glabrata chorioamnionitis is uncommon and associated with poor fetal outcomes. We present a case of C. glabrata chorioamnionitis of a dichorionic diamniotic pregnancy conceived by fresh embryo transfer. Despite antifungal therapy with amphotericin B, spontaneous miscarriage of both twins occurred. The mother otherwise recovered uneventfully. Our case highlights the high fetal mortality associated with C. glabrata chorioamnionitis and the challenges of antifungal treatment in pregnancy. We recommend a low threshold of suspicion for Candida infection in pregnancy, notably those involving transvaginal uterine instrumentation such as in vitro fertilisation. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Databáze: | MEDLINE |
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