Propensity-score-matching-based analysis of laparoscopic gastrectomy with neoadjuvant chemotherapy for gastric carcinoma.

Autor:	Furuta S; Department of Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan., Uyama I; Department of Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan., Morise Z; Department of Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Jazyk:	angličtina
Zdroj:	Fujita medical journal [Fujita Med J] 2021; Vol. 7 (2), pp. 50-53. Date of Electronic Publication: 2020 Oct 10.
DOI:	10.20407/fmj.2020-007
Abstrakt:	Objectives: Neoadjuvant chemotherapy (NAC) is widely accepted as a potential treatment for advanced gastric cancer (AGC). Laparoscopic gastrectomy (LG) has recently been performed for advanced gastric cancer and could lead to improved adherence to multimodal treatment. In the present study, we compared the feasibility and outcomes of LG in patients with or without NAC in our institution. Methods: We assessed patients who underwent LG with (n=185) or without (n=1204) NAC between 1997 and 2013. We used propensity score matching to evaluate perioperative short-term outcomes and long-term outcome. Results: We used propensity score matching by patient background and treatment-rerated factors to establish two groups of 157 patients with or without NAC. There were no significant differences in perioperative short-term outcomes or long-term outcome between the groups. Conclusions: LG for selected patients with NAC is feasible and safe but has no long-term survival benefit. Competing Interests: The authors have no conflicts of interest directly relevant to the content of this article.
Databáze:	MEDLINE
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