The Role of Pneumococcal Pneumonia among Community-Acquired Pneumonia in Adult Turkish Population: TurkCAP Study.

Autor: Şenol E; Department of Infectious Diseases, Gazi University, Faculty of Medicine, Ankara, Turkey., Çilli A; Department of Pulmonary Diseases, Akdeniz University, Faculty of Medicine, Antalya, Turkey., Günen H; Department of Pulmonary Diseases, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey., Şener A; Department of Infectious Diseases and Clinical Microbiology, 18 Mart University, Faculty of Medicine, Çanakkale, Turkey., Dumlu R; Department of Infectious Diseases and Clinical Microbiology, 18 Mart University, Faculty of Medicine, Çanakkale, Turkey., Ödemiş A; Department of Pulmonary Diseases, Akdeniz University, Faculty of Medicine, Antalya, Turkey., Topçu AF; Department of Pulmonary Diseases, Dicle University, Faculty of Medicine, Diyarbakır, Turkey., Yıldız Y; Department of Infectious Diseases and Clinical Microbiology, Mardin State Hospital, Mardin, Turkey., Güner R; Department of Infectious Diseases and Clinical Microbiology, Ankara Atatürk Training and Research Hospital, Ankara, Turkey., Özhasenekler A; Department of Emergency Medicine, Ankara Atatürk Training and Research Hospital, Ankara, Turkey., Mutlu B; Department of Infectious Diseases, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey., Köktürk N; Department of Pulmonary Diseases, Gazi University, Faculty of Medicine, Ankara, Turkey., Sevimli N; Department of Pulmonary Diseases, Gazi University, Faculty of Medicine, Ankara, Turkey., Baykam N; Department of Infectious Diseases and Clinical Microbiology, Hitit University, Faculty of Medicine, Çorum, Turkey., Yapar D; Department of Infectious Diseases and Clinical Microbiology, Hitit University, Faculty of Medicine, Çorum, Turkey., Ekin S; Department of Pulmonary Diseases, Yüzüncü Yıl University, Faculty of Medicine, Van, Turkey., Polatlı M; Department of Pulmonary Diseases, Adnan Menderes University, Faculty of Medicine, Aydın, Turkey., Gök ŞE; Department of Infectious Diseases and Clinical Microbiology, Bozok University, Faculty of Medicine, Yozgat, Turkey., Kılınç O; Department of Pulmonary Diseases, Dokuz Eylül University, Faculty of Medicine, Izmir, Turkey., Sayıner A; Department of Pulmonary Diseases, Ege University, Faculty of Medicine, Izmir, Turkey., Karaşahin Ö; Department of Infectious Diseases and Clinical Microbiology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey., Çuhadaroğlu Ç; Department of Pulmonary Diseases and Sleep Disorder, Acıbadem Health Group Maslak Hospital, Istanbul, Turkey., Sesin Kocagöz A; Department of Infectious Diseases and Clinical Microbiology, Acıbadem Health Group Maslak Hospital, Istanbul, Turkey., Togan T; Department of Infectious Diseases and Clinical Microbiology, Başkent University Konya Hospital, Konya, Turkey., Arpağ H; Department of Pulmonary Diseases, Sutcu Imam University, Faculty of Medicine, Kahramanmaraş, Turkey., Katı H; Department of Infectious Diseases, Gazi University, Faculty of Medicine, Ankara, Turkey., Köksal İ; Department of Infectious Diseases, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey., Aksoy F; Department of Infectious Diseases, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey., Hasanoğlu C; Department of Pulmonary Diseases, Ankara Atatürk Training and Research Hospital, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Turkish thoracic journal [Turk Thorac J] 2021 Jul; Vol. 22 (4), pp. 339-345.
DOI: 10.5152/TurkThoracJ.2021.20223
Abstrakt: Objective: To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired pneumonia (CAP) in Turkey and to investigate and compare features of PP and non-PP CAP patients.
Material and Methods: This multicenter, non-interventional, prospective, observational study included adult CAP patients (age ≥ 18 years). Diagnosis of PP was based on the presence of at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum culture or urinary antigen test [UAT]) in patients with radiographic findings of pneumonia.
Results: Four hundred sixty-five patients were diagnosed with CAP, of whom 59 (12.7%) had PP. The most common comorbidity was chronic obstructive pulmonary disease (30.1%). The mean age, smoking history, presence of chronic neurological disease, and CURB-65 score were significantly higher in PP patients, when compared to non-PP patients. In PP patients, 84.8% were diagnosed based ony on the UAT. The overall rate of PP patients among CAP was calculated as 22.8% considering the UAT sensitivity ratio of 63% (95% confidence interval: 45-81). The rate of intensive care treatment was higher in PP patients (P = .007). While no PP patients were vaccinated for pneumococcus, 3.8% of the non-PP patients were vaccinated (P = .235). Antibiotic use in the preceding 48 hours was higher in the non-PP group than in the PP group (31.8% vs. 11.1%, P = .002). The CURB-65 score and the rate of patients requiring inpatient treatment according to this score were higher in the PP group.
Conclusion: The facts that PP patients were older and required intensive care treatment more frequently as compared to non-PP patients underline the burden of PP.
Databáze: MEDLINE