Infective Endocarditis Outcomes in Jeddah City, Saudi Arabia.

Autor:	Bogari MH; Medicine and Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Jarwan AS; Medicine and Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Abukhodair AO; Medicine and Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Alzahrani BA; Medicine and Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Alsayegh JA; Medicine and Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Al-Kathiri A; Laboratory Medicine/Molecular Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU., Kinsara AJ; Cardiology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Dec 20; Vol. 13 (12), pp. e20556. Date of Electronic Publication: 2021 Dec 20 (Print Publication: 2021).
DOI:	10.7759/cureus.20556
Abstrakt:	Objectives: This study aimed to analyze all the reported cases of definitive infective endocarditis, based on the modified Duke criteria in a tertiary hospital over the past five years, focusing on the causative organism/s, predisposing factors, and outcomes. Methods: This is a cross-sectional retrospective study. Patients with a confirmed diagnosis of infective endocarditis using modified Duke criteria were included. The demographic data, predisposing factors, the causative microorganisms, laboratory and echocardiography results, and treatment were collected. Results: In total, 37 patients were identified, 22 were male, and the median age was 59 years. Native valve endocarditis was found in 29 (78.3%) patients. The most frequently involved valves were the mitral valve in eight (42.1%) and aortic valve in six (31.6%) patients. Fever occurred in 22 patients (59.5%). The most frequent organisms were Staphylococcus aureus in 14 (37.4%) patients, coagulase-negative staphylococci in seven (18.9%) patients, and streptococci in seven (18.9%) patients. The majority (n=27) of the patients (72.97%) were treated medically, with 10 (27.02%) requiring in-hospital surgical intervention. The in-hospital mortality rate was 24.3%. Late presentation, reluctance to undergo surgery, and the past history of rheumatic fever were the contributing factors. Conclusion: Native valve endocarditis is the major type of infective endocarditis. The most frequent organisms were Staphylococcus aureus , Streptococcus, and coagulase-negative staphylococci. In our study, infective endocarditis was more common among males, surgical intervention was low, and a high in-hospital mortality rate was noted in our series. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Bogari et al.)
Databáze:	MEDLINE
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