Subfoveal Choroidal Thickness and Ganglion Cell Complex in Children with Type 1 Diabetes Mellitus Without Diabetic Retinopathy.

Autor:	Bayat AH; Department of Ophthalmology, University of Health Sciences, Okmeydani Traning and Research Hospital, Istanbul, Turkey., Cakir A; Department of Ophthalmology, University of Health Sciences, Okmeydani Traning and Research Hospital, Istanbul, Turkey., Bezen D; Department of Pediatric Endocrinology, University of Health Sciences, Okmeydani Traning and Research Hospital, Istanbul, Turkey., Elcioglu MN; Department of Ophthalmology, University of Health Sciences, Okmeydani Traning and Research Hospital, Istanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Beyoglu eye journal [Beyoglu Eye J] 2020 Dec 28; Vol. 5 (3), pp. 174-177. Date of Electronic Publication: 2020 Dec 28 (Print Publication: 2020).
DOI:	10.14744/bej.2020.50470
Abstrakt:	Objectives: This study is an analysis of the subfoveal choroidal thickness (SFCT) and ganglion cell complex (GCC) in children who have type 1 diabetes mellitus (T1D) without diabetic retinopathy. Methods: In all, 36 right eyes of 36 patients with T1D and 36 right eyes of sex- and age-matched healthy subjects were included in this prospective study. SFCT and GCC measurements were obtained using spectral domain optical coherence tomography (SD-OCT). Correlations between SCFT, GCC and duration of T1D, glycated hemoglobin, and age were also investigated. Results: The mean SFCT was 342.1±42.3 μm in the T1D group and 354±70.8 μm in the control group (p>0.05). There was no significant difference between the groups in the GCC superior and inferior retina values. The average GCC was thinner in the T1D group (T1D group: 88.11±14.93 μm, control group: 103.39±15.65 μm; p=0.005). The mean central retinal thickness (CRT) was decreased in the T1D group (T1D group: 248.1±16.5 μm, control group: 262.1±18.3 μm; p=0.021). Conclusion: The mean SFCT was not significantly different in diabetic children compared with healthy eyes. The CRT and average GCC thickness were lower in children with T1D. SD-OCT can reveal neurodegenerative changes that may occur before vascular changes in diabetic children. Competing Interests: Conflict of Interest: None declared. (Copyright: © 2020 by Beyoglu Eye Training and Research Hospital.)
Databáze:	MEDLINE
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