Isolated Myeloid Sarcoma and Intracardiac Thrombus Resulting in Superior Mediastinal Syndrome.

Autor: Roy PS; Hematology-Oncology Unit, Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India., Vohra V; Hematology-Oncology Unit, Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India., Jain R; Hematology-Oncology Unit, Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India., Singhal KK; Pulmonology Unit, Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Mahajan S; Cardiovascular and Thoracic Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Chatterjee D; Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Saxena AK; Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Rohilla M; Cytology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Bansal D; Hematology-Oncology Unit, Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. deepakbansaldr@gmail.com.
Jazyk: angličtina
Zdroj: Indian journal of pediatrics [Indian J Pediatr] 2022 Jun; Vol. 89 (6), pp. 591-593. Date of Electronic Publication: 2022 Jan 29.
DOI: 10.1007/s12098-021-04056-1
Abstrakt: Superior mediastinal syndrome (SMS) is a relatively common emergency in the practice of Pediatric Oncology. It typically results from the compression of large airways and superior vena cava by a swiftly growing mass. T-lineage acute lymphoblastic leukemia or lymphoma, neuroblastoma, and germ cell tumor are the common etiologies of SMS in children. Occasionally, SMS can be an unexpected presentation of less common childhood cancers and a surprise for the diagnostic and treating teams. The present paper reports the diagnostic and therapeutic challenge of managing a 9-y-old boy with SMS resulting from mediastinal myeloid sarcoma. The presence of a sizeable intracardiac thrombus, in addition, contributed to the SMS. The initial pleural fluid cytology and image-guided fine-needle aspiration cytology of the mediastinal mass were nondiagnostic. A thoracotomy was subsequently performed to debulk the tumor for symptomatic relief and obtain tissue for diagnosis.
(© 2022. Dr. K C Chaudhuri Foundation.)
Databáze: MEDLINE
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