The OLGA-OLGIM staging and the interobserver agreement for gastritis and preneoplastic lesion screening: a cross-sectional study.

Autor: Salazar BE; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia. beatriz.salazar@udea.edu.co., Pérez-Cala T; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia., Gomez-Villegas SI; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia., Cardona-Zapata L; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia., Pazos-Bastidas S; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia., Cardona-Estepa A; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia., Vélez-Gómez DE; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia., Justinico-Castro JA; Department of Pathology, School of Medicine, University of Antioquia, Medellín, Colombia., Bernal-Cobo A; Department of Pathology, School of Medicine, University of Antioquia, Medellín, Colombia., Dávila-Giraldo HA; Department of Pathology, School of Medicine, University of Antioquia, Medellín, Colombia., Benítez-Guerra JC; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia.; Promedan IPS, Medellín, Colombia., Valencia-Cárdenas JT; IPS Universitaria, University of Antioquia, Medellín, Colombia., Ospina EJ; Somer Clinic, Rionegro, Colombia., Castaño-Llano R; Cancer Institute, Las Americas Clinic, Medellín, Colombia., Bravo MM; Cancer Biology Research Group, National Cancer Institute, Bogotá, Colombia., Cataño-Correa JC; Internal Medicine Infectious Disease Section, University of Antioquia, Medellín, Colombia., Zabaleta J; Department of Integrative Oncology and Department of Pediatrics, Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Trespalacios-Rangel AA; Infectious Disease Group, Department of Microbiology, Pontificia Universidad Javeriana, Bogotá, Colombia., Cock-Botero AM; Cytology and Pathology Unit, Las Vegas Clinic, Medellín, Colombia., Roldán-Pérez MI; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia.; Department of Pathology, School of Medicine, University of Antioquia, Medellín, Colombia., Martínez A; Bacteria & Cancer Group, Department of Microbiology, School of Medicine, University of Antioquia, Medellín, Colombia.
Jazyk: angličtina
Zdroj: Virchows Archiv : an international journal of pathology [Virchows Arch] 2022 Apr; Vol. 480 (4), pp. 759-769. Date of Electronic Publication: 2022 Jan 28.
DOI: 10.1007/s00428-022-03286-8
Abstrakt: Stomach cancer (SC) incidence and mortality are relevant public health issues worldwide. In Colombia, screening for preneoplastic lesions (PNL) and the presence of H. pylori is not routinely performed. Therefore, the aim of this study was to evaluate OLGA-OLGIM staging and the interobserver agreement in gastritis and preneoplastic lesions in patients with gastroduodenal symptoms from Colombia. A cross-sectional study was conducted in 272 patients with gastroduodenal symptoms. Gastric biopsies were taken following the Updated Sydney System with the OLGA-OLGIM classification, and the results were evaluated by two pathologists. Chronic gastritis and PNL were reported in 76% and 24% of the patients, respectively. Furthermore, 25% of the patients with PNL displayed gastric atrophy (GA) and 75% intestinal metaplasia (IM). Agreement in the histopathological reading for IM was good, whereas for OLGA was variable, and for the H. pylori quantity was poor. OLGA-OLGIM stages 0-II were the most frequent (96%), while stage III (4%) and SC (4%) were the least frequent. Age and coffee consumption were associated with a higher prevalence of PNL. This work determined that 4% of the population is at high risk of developing SC and would benefit from follow-up studies. Reinforcement of training programs to improve the agreement in histopathology readings is required.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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