Amount and intensity effects of exercise training alone versus a combined diet and exercise lifestyle intervention on health-related quality of life in the STRRIDE-PD randomized trial.
Autor: | Collins KA; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA katherine.collins791@duke.edu., Ross LM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA., Piner LW; Emeritis, Duke University School of Medicine, Durham, North Carolina, USA., Fos LB; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA., Slentz CA; Emeritis, Duke University School of Medicine, Durham, North Carolina, USA., Bateman LA; Department of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Willis LH; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA., Bales CW; Department of Geriatrics, Duke University School of Medicine, Durham, North Carolina, USA.; Geriatric Research Education and Clinical Center, Durham VA Medical Center, Durham, North Carolina, USA., Siegler IC; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA., Wolever RQ; Department of Physical Medicine and Rehabilitation, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Huffman KM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Rheumatology/Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Kraus WE; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Cardiology/Medicine, Duke University School of Medicine, Durham, North Carolina, USA. |
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Jazyk: | angličtina |
Zdroj: | BMJ open diabetes research & care [BMJ Open Diabetes Res Care] 2022 Jan; Vol. 10 (1). |
DOI: | 10.1136/bmjdrc-2021-002584 |
Abstrakt: | Introduction: To determine the relative contributions of various amounts and intensities of exercise alone to a combined lifestyle intervention on health-related quality of life (HrQoL) measures. Research Design and Methods: Participants (n=162) were sedentary, overweight/obese, with pre-diabetes, and randomized to one of four 6-month interventions: (1) high amount/moderate intensity exercise-energy expenditure of 16 kcal/kg of body weight/week (KKW) at 50% oxygen consumption (V̇O Results: Across the intervention, all groups (p<0.05) improved the physical component, SPF, and SPA scores. Only the low/moderate/diet group (p<0.001) significantly improved the mental component score. The high/vigorous group achieved 84.5% of the low/moderate/diet group effect for change in physical component score, and the low/moderate group achieved 83.7% of the low/moderate/diet group effect for change in mental component score. Conclusions: In general, a low amount of moderate intensity exercise combined with diet was the most effective intervention for improving HrQoL. Of the exercise-only interventions, vigorous intensity exercise provided the greatest impact on changes in physical function. On the other hand, low amounts of moderate intensity exercise provided the greatest impact on mental well-being, potentially being a more attainable exercise dose for previously sedentary individuals with pre-diabetes to achieve. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
Databáze: | MEDLINE |
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